Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 3110
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28154(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50: 13nM EC50:  120nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28138(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 21nM EC50:  430nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28141(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50: 26nM EC50:  360nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28152(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50: 27nM EC50:  210nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28154(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50: 29nM EC50:  370nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28142(methyl (2S)-2-[(3-bromobenzene)sulfonyl]-2-[(2R)-7...)
Affinity DataIC50: 30nM EC50:  150nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28137(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 31nM EC50:  1.81E+3nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28141(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50: 49nM EC50:  1.35E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28139(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50: 56nM EC50:  160nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28139(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50: 62nM EC50:  1.07E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28149(2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50: 65nM EC50:  240nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28138(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 73nM EC50:  1.39E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28150(2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50: 83nM EC50:  92nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28155(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50: 100nM EC50:  160nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28137(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 100nM EC50:  2.17E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28142(methyl (2S)-2-[(3-bromobenzene)sulfonyl]-2-[(2R)-7...)
Affinity DataIC50: 100nM EC50:  850nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28151(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50: 150nM EC50:  76nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28134(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 150nM EC50:  1.70E+3nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28147((2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1H,2H,3H...)
Affinity DataIC50: 170nM EC50:  110nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28152(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50: 210nM EC50:  1.09E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28150(2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50: 290nM EC50:  430nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28151(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50: 300nM EC50:  890nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28131(methyl (2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1...)
Affinity DataIC50: 350nM EC50:  250nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28145(methyl (2S)-2-(benzenesulfonyl)-2-[(4R)-11-chloro-...)
Affinity DataIC50: 400nM EC50:  370nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28148(2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50: 490nM EC50:  170nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28143(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50: 500nM EC50:  340nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28135(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 540nM EC50:  2.08E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28140(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50: 700nM EC50:  190nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28135(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 800nM EC50:  1.53E+3nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28134(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 820nM EC50:  2.18E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28149(2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50: 920nM EC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28131(methyl (2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1...)
Affinity DataIC50: 1.10E+3nM EC50:  1.60E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28140(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50: 1.21E+3nM EC50:  840nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28153(methyl 5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2...)
Affinity DataIC50: 1.63E+3nM EC50:  1.26E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28147((2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1H,2H,3H...)
Affinity DataIC50: 1.79E+3nM EC50:  1.09E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28136(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 2.25E+3nM EC50:  2.30E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28148(2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50: 2.30E+3nM EC50:  770nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28145(methyl (2S)-2-(benzenesulfonyl)-2-[(4R)-11-chloro-...)
Affinity DataIC50: 2.58E+3nM EC50:  4.23E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28146((2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1H,2H,3H...)
Affinity DataIC50: 2.70E+3nM EC50:  1.55E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28132(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 3.30E+3nM EC50:  5.81E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28132(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 3.30E+3nM EC50:  370nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28136(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 3.42E+3nM EC50:  3.16E+3nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28146((2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1H,2H,3H...)
Affinity DataIC50: 3.87E+3nM EC50:  400nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28144(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50: 3.95E+3nM EC50:  270nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28144(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50: 1.22E+4nM EC50:  2.75E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28143(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50: 2.00E+4nM EC50:  1.07E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28133(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 3.12E+4nM EC50: >4.00E+4nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

LigandPNGBDBM28133(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 8.79E+4nM EC50:  5.80E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed