Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 4989
TargetCarbonic anhydrase 2(Human)
Antibiotics Laboratory

LigandPNGBDBM84663(Piperazine moiety, 3)
Affinity DataIC50: 48nM Kd:  29nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Antibiotics Laboratory

LigandPNGBDBM84666(Piperazine moiety, 6)
Affinity DataIC50: 72nM Kd:  100nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Antibiotics Laboratory

LigandPNGBDBM84665(Piperazine moiety, 5)
Affinity DataIC50: 137nM Kd:  208nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Antibiotics Laboratory

LigandPNGBDBM84662(4-Fuloro sulfonamide, C)
Affinity DataIC50: 203nM Kd:  435nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Antibiotics Laboratory

LigandPNGBDBM84664(Piperazine moiety, 4)
Affinity DataIC50: 299nM Kd:  426nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed