Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50004467
TargetHistone deacetylase(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258646(N1-(4-(3-aminophenyl)thiazol-2-yl)-N8-hydroxyoctan...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258645(N1-hydroxy-N8-(4-phenylthiazol-2-yl)octanediamide ...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258646(N1-(4-(3-aminophenyl)thiazol-2-yl)-N8-hydroxyoctan...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50483197(CHEMBL1630846)
Affinity DataIC50: 44nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258647(N1-(biphenyl-4-yl)-N8-hydroxyoctanediamide | CHEMB...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50214441(octanedioic acid [2'-(2-amino-3-phenylpropionylami...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50483198(Octanedioic acid adamantan-1-ylamide hydroxyamide ...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed