Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50038807
TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataEC50:  45nMAssay Description:Agonist activity against mu opioid receptor expressed in CHO cells assessed as stimulation [35S]GTPgammaS binding relative to basal levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266857((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50247803(Beta-Funeltrexamine | beta-funaltrexamine | methyl...)
Affinity DataKi:  0.410nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50247803(Beta-Funeltrexamine | beta-funaltrexamine | methyl...)
Affinity DataKi:  0.940nMAssay Description:Displacement of [3H]norBNI from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266887((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266858((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266827(D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr | CHEMBL500766)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266888((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]norBNI from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266859((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266887((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]NTI from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266857((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]norBNI from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50247803(Beta-Funeltrexamine | beta-funaltrexamine | methyl...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]NTI from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266918((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]norBNI from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266858((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]norBNI from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266859((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]norBNI from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266887((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  67nMAssay Description:Displacement of [3H]norBNI from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266886((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataKi:  117nMAssay Description:Displacement of [3H]NTI from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266857((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  117nMAssay Description:Displacement of [3H]NTI from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266860((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  123nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266888((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  148nMAssay Description:Displacement of [3H]norBNI from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266858((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]NTI from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266918((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  225nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266859((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  405nMAssay Description:Displacement of [3H]NTI from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266860((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  586nMAssay Description:Displacement of [3H]norBNI from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266888((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  818nMAssay Description:Displacement of [3H]NTI from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266918((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi:  907nMAssay Description:Displacement of [3H]NTI from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266827(D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr | CHEMBL500766)
Affinity DataKi:  1.01E+3nMAssay Description:Displacement of [3H]norBNI from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266827(D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr | CHEMBL500766)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [3H]NTI from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266886((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]NTI from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266860((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]NTI from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50266886((1S,5R,13R,17S)-4-(cyclopropylmethyl)-10-hydroxy-1...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]norBNI from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed