Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50028228
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248503(N-(diaminomethylene)-2-(2,5-dichlorophenyl)-5-meth...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248341(N-(diaminomethylene)-2-(2,5-dichlorophenyl)-5-meth...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248408(N-(diaminomethylene)-2-(2,5-dimethylphenyl)-5-meth...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248404(2-(5-chloro-2-methoxyphenyl)-N-(diaminomethylene)-...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248340(N-(diaminomethylene)-2-(2,3-dichlorophenyl)-5-meth...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248342(N-(diaminomethylene)-2-(3,5-dichlorophenyl)-5-meth...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248405(N-(diaminomethylene)-2-(5-fluoro-2-methoxyphenyl)-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248504(N-(diaminomethylene)-2-(3,5-dichlorophenyl)-5-meth...)
Affinity DataIC50: 890nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248174(N-(diaminomethylene)-2-(2,5-dimethylphenyl)-5-meth...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248286(2-(2-chlorophenyl)-N-(diaminomethylene)-5-methyl-1...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248461(2-(3-chlorophenyl)-N-(diaminomethylene)-5-methylox...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248221(N-(diaminomethylene)-2-(3,4-dimethoxyphenyl)-5-met...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248143(N-(diaminomethylene)-5-methyl-2-o-tolyl-1H-imidazo...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248285(N-(diaminomethylene)-2-(3,5-difluorophenyl)-5-meth...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248459(N-(diaminomethylene)-2-(2,5-difluorophenyl)-5-meth...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248284(N-(diaminomethylene)-2-(2,5-difluorophenyl)-5-meth...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248176(N-(diaminomethylene)-2-(2-methoxyphenyl)-5-methyl-...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248460(N-(diaminomethylene)-2-(3,5-difluorophenyl)-5-meth...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248177(N-(diaminomethylene)-2-(3-methoxyphenyl)-5-methyl-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248458(N-(diaminomethylene)-2-(3-fluorophenyl)-5-methylox...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248223(N-(diaminomethylene)-2-(3-fluorophenyl)-5-methyl-1...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248338(2-(3-chlorophenyl)-N-(diaminomethylene)-5-methyl-1...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248175(N-(diaminomethylene)-2-(3,5-dimethylphenyl)-5-meth...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248407(N-(diaminomethylene)-5-methyl-2-m-tolyloxazole-4-c...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248283(N-(diaminomethylene)-2-(2,3-difluorophenyl)-5-meth...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248457(N-(diaminomethylene)-2-(3,5-dimethylphenyl)-5-meth...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248222(N-(diaminomethylene)-2-(2-fluorophenyl)-5-methyl-1...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248406(N-(diaminomethylene)-5-methyl-2-phenyloxazole-4-ca...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248142(N-(diaminomethylene)-5-methyl-2-phenyl-1H-imidazol...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248144(N-(diaminomethylene)-5-methyl-2-m-tolyl-1H-imidazo...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248462(2-(4-chlorophenyl)-N-(diaminomethylene)-5-methylox...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248220(N-(diaminomethylene)-2-(2,3-dimethoxyphenyl)-5-met...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248145(N-(diaminomethylene)-5-methyl-2-p-tolyl-1H-imidazo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248173(N-(diaminomethylene)-2-(2,3-dimethylphenyl)-5-meth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248339(2-(4-chlorophenyl)-N-(diaminomethylene)-5-methyl-1...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248282(N-(diaminomethylene)-2-(4-fluorophenyl)-5-methyl-1...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50248219(N-(diaminomethylene)-2-(4-methoxyphenyl)-5-methyl-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed