Compile Data Set for Download or QSAR
Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 50028177
LigandPNGBDBM50248471(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248472(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248519(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248518(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248521(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248569((1-(((R)-3-methyl-4-(4-((S)-1,1,1-trifluoro-2-hydr...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248520(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248469(2-(4-((R)-4-(2,2-difluoro-2-(pyridin-4-yl)ethyl)-2...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248310((R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(3-(...)
Affinity DataIC50: 1nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248470(2-(4-((R)-4-(2,2-difluoro-2-(pyridin-3-yl)ethyl)-2...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248568(4-(1-(((3R)-3-methyl-4-(4-(1,1,1-trifluoro-2-hydro...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248427(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-(2-(pyridin-3...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248566(1-(((3R)-3-methyl-4-(4-(1,1,1-trifluoro-2-hydroxyp...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248252(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-(2-(pyridin-4...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248567(1-(((3R)-3-methyl-4-(4-(1,1,1-trifluoro-2-hydroxyp...)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM32573(CHEMBL427896 | arylsulfonylpiperazine, 45)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248308((2R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(1-...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248370((2R)-2-methyl-4-(2-(pyridin-4-yl)ethyl)-1-(4-(1,1,...)
Affinity DataIC50: 4nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248425((R)-(1-(4-(2-methyl-4-(2-(pyridin-4-yl)ethyl)piper...)
Affinity DataIC50: 4nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248255((R)-2-(4-(2-methyl-4-(2-(pyridin-4-yl)ethyl)pipera...)
Affinity DataIC50: 5nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248309((R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(2-(...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248254((R)-4-((4-(4-tert-butylphenylsulfonyl)-3-methylpip...)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50247925(1-(((R)-3-methyl-4-(4-((R)-1,1,1-trifluoro-2-hydro...)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248426((R)-4-((1-(4-(2-methyl-4-(2-(pyridin-4-yl)ethyl)pi...)
Affinity DataIC50: 8nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248428(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-(2-(pyridin-2...)
Affinity DataIC50: 10nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248311((R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(pyr...)
Affinity DataIC50: 11.3nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248371(1-(4-((R)-2-methyl-4-(2-(pyridin-4-yl)ethyl)pipera...)
Affinity DataIC50: 12nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248569((1-(((R)-3-methyl-4-(4-((S)-1,1,1-trifluoro-2-hydr...)
Affinity DataIC50: 14nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248372((2R)-1-(4-(1-fluoroethyl)phenylsulfonyl)-2-methyl-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248252(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-(2-(pyridin-4...)
Affinity DataIC50: 21nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248566(1-(((3R)-3-methyl-4-(4-(1,1,1-trifluoro-2-hydroxyp...)
Affinity DataIC50: 25.4nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248519(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248472(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248427(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-(2-(pyridin-3...)
Affinity DataIC50: 29nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248373((R)-1-(4-(1,1-difluoroethyl)phenylsulfonyl)-2-meth...)
Affinity DataIC50: 30nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248521(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248469(2-(4-((R)-4-(2,2-difluoro-2-(pyridin-4-yl)ethyl)-2...)
Affinity DataIC50: 33nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248471(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50: 33nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248520(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248307((R)-1-(4-(2-fluoropropan-2-yl)phenylsulfonyl)-2-me...)
Affinity DataIC50: 36nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248518(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50: 43nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248310((R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(3-(...)
Affinity DataIC50: 47nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248425((R)-(1-(4-(2-methyl-4-(2-(pyridin-4-yl)ethyl)piper...)
Affinity DataIC50: 55nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM32573(CHEMBL427896 | arylsulfonylpiperazine, 45)
Affinity DataIC50: 57nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248309((R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(2-(...)
Affinity DataIC50: 61nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248255((R)-2-(4-(2-methyl-4-(2-(pyridin-4-yl)ethyl)pipera...)
Affinity DataIC50: 69nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248371(1-(4-((R)-2-methyl-4-(2-(pyridin-4-yl)ethyl)pipera...)
Affinity DataIC50: 70nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248370((2R)-2-methyl-4-(2-(pyridin-4-yl)ethyl)-1-(4-(1,1,...)
Affinity DataIC50: 71nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248470(2-(4-((R)-4-(2,2-difluoro-2-(pyridin-3-yl)ethyl)-2...)
Affinity DataIC50: 78nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248254((R)-4-((4-(4-tert-butylphenylsulfonyl)-3-methylpip...)
Affinity DataIC50: 78nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Displayed 1 to 50 (of 71 total ) | Next | Last >>
Jump to: