Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 3031
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27048(3-{[(1R,2S,5S)-3-[(2S)-2-({[(2S)-1-(1,1-dioxo-2,3-...)
Affinity DataKi:  0.900nM ΔG°:  -52.5kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27043(3-{[(1R,2S,5S)-3-[(2S)-2-({[(2S)-1-(1,1-dioxo-2H,3...)
Affinity DataKi:  3nM ΔG°:  -49.5kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27039(3-{[(1R,2S,5S)-3-[(2S)-2-({[(2S)-1-(1,1-dioxo-2,3-...)
Affinity DataKi:  3nM ΔG°:  -49.5kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27049(3-{[(1R,2S,5S)-3-[(2S)-2-({[(2S)-1-(1,1-dioxo-2,3-...)
Affinity DataKi:  5nM ΔG°:  -48.2kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27045(3-{[(1R,2S,5S)-3-[(2S)-2-({[(2S)-1-(1,1-dioxo-2,3-...)
Affinity DataKi:  5nM ΔG°:  -48.2kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27033(3-{[(1R,2S,5S)-3-[(2S)-2-({[(2S)-1-(1,1-dioxo-1,2-...)
Affinity DataKi:  6nM ΔG°:  -47.7kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27044(3-{[(1R,2S,5S)-3-[(2S)-2-cyclohexyl-2-({[(2S)-1-(1...)
Affinity DataKi:  7nM ΔG°:  -47.3kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27047(4-cyclopropyl-3-{[(1R,2S,5S)-3-[(2S)-2-({[(2S)-1-(...)
Affinity DataKi:  7nM ΔG°:  -47.3kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27037(3-{[(1R,2S,5S)-3-[(2S)-2-({[(2S)-1-(1,1-dioxo-2H,3...)
Affinity DataKi:  10nM ΔG°:  -46.4kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27032(3-{[(1R,2S,5S)-3-[(2S)-2-({[(2S)-1-(1,1-dioxo-1,2-...)
Affinity DataKi:  11nM ΔG°:  -46.2kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27042(3-{[(1R,2S,5S)-3-[(2S)-2-cyclohexyl-2-({[(2S)-1-(1...)
Affinity DataKi:  14nM ΔG°:  -45.6kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27036(3-{[(1R,2S,5S)-3-[(2S)-2-({[(2S)-3,3-dimethyl-1-(6...)
Affinity DataKi:  14nM ΔG°:  -45.6kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27041(3-{[(1R,2S,5S)-3-[(2S)-2-({[(2S)-3,3-dimethyl-1-(1...)
Affinity DataKi:  15nM ΔG°:  -45.4kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27040(3-{[(1R,2S,5S)-3-[(2S)-2-({[(1S)-1-cyclohexyl-2-(1...)
Affinity DataKi:  18nM ΔG°:  -44.9kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27046(4-cyclobutyl-3-{[(1R,2S,5S)-3-[(2S)-2-({[(2S)-1-(1...)
Affinity DataKi:  30nM ΔG°:  -43.7kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27034(3-{[(1R,2S,5S)-3-[(2S)-2-({[(1S)-1-cyclohexyl-2-(1...)
Affinity DataKi:  30nM ΔG°:  -43.7kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27038(3-{[(1R,2S,5S)-3-[(2S)-2-[({1-[(1,1-dioxo-2H,3H-1,...)
Affinity DataKi:  41nM ΔG°:  -42.9kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27035(3-{[(1R,2S,5S)-3-[(2S)-2-({[(2S)-1-(1,1-dioxo-1,2,...)
Affinity DataKi:  59nM ΔG°:  -42.0kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed