Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50028094
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255909(6-(4-(5-fluoro-6-methylpyridin-2-yl)-2-(4-methylpi...)
Affinity DataEC50:  344nMAssay Description:Inhibition of TGFBR1 transfected in human HepG2 cells after 24 hrs by plasminogen activator inhibitor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255906(N-(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin...)
Affinity DataEC50:  1.48E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255179(N-(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin...)
Affinity DataEC50:  1.48E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255957(1-(4-(5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(5-...)
Affinity DataEC50:  1.42E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255230(N-(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin...)
Affinity DataEC50:  1.35E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255909(6-(4-(5-fluoro-6-methylpyridin-2-yl)-2-(4-methylpi...)
Affinity DataEC50:  1.09E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255957(1-(4-(5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(5-...)
Affinity DataEC50:  1.22E+3nMAssay Description:Inhibition of TGFBR1 transfected in human HepG2 cells after 24 hrs by plasminogen activator inhibitor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255908(4-(5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(5-flu...)
Affinity DataEC50:  513nMAssay Description:Inhibition of TGFBR1 transfected in human HepG2 cells after 24 hrs by plasminogen activator inhibitor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255958(6-(4-(5-fluoro-6-methylpyridin-2-yl)-2-(4-(methyls...)
Affinity DataEC50:  414nMAssay Description:Inhibition of TGFBR1 transfected in human HepG2 cells after 24 hrs by plasminogen activator inhibitor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255179(N-(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin...)
Affinity DataEC50:  180nMAssay Description:Inhibition of TGFBR1 transfected in human HepG2 cells after 24 hrs by plasminogen activator inhibitor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255227(N-(5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(6-met...)
Affinity DataEC50:  165nMAssay Description:Inhibition of TGFBR1 transfected in human HepG2 cells after 24 hrs by plasminogen activator inhibitor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255230(N-(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin...)
Affinity DataEC50:  156nMAssay Description:Inhibition of TGFBR1 transfected in human HepG2 cells after 24 hrs by plasminogen activator inhibitor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255906(N-(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin...)
Affinity DataEC50:  148nMAssay Description:Inhibition of TGFBR1 transfected in human HepG2 cells after 24 hrs by plasminogen activator inhibitor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255228(N-(5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(5-flu...)
Affinity DataEC50:  111nMAssay Description:Inhibition of TGFBR1 transfected in human HepG2 cells after 24 hrs by plasminogen activator inhibitor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255231(N-(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin...)
Affinity DataEC50:  61nMAssay Description:Inhibition of TGFBR1 transfected in human HepG2 cells after 24 hrs by plasminogen activator inhibitor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255231(N-(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin...)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255960(4-(6-methylpyridin-2-yl)-5-(quinoxalin-6-yl)thiazo...)
Affinity DataEC50:  2.20E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255228(N-(5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(5-flu...)
Affinity DataEC50:  2.81E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255958(6-(4-(5-fluoro-6-methylpyridin-2-yl)-2-(4-(methyls...)
Affinity DataEC50:  4.12E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255908(4-(5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(5-flu...)
Affinity DataEC50:  4.63E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255960(4-(6-methylpyridin-2-yl)-5-(quinoxalin-6-yl)thiazo...)
Affinity DataEC50:  80nMAssay Description:Inhibition of TGFBR1 transfected in human HepG2 cells after 24 hrs by plasminogen activator inhibitor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255227(N-(5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(6-met...)
Affinity DataEC50:  5.78E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255959(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin-6-...)
Affinity DataIC50: 33.5nMAssay Description:Inhibition of TGFBR1 transfected in human HepG2 cells after 24 hrs by plasminogen activator inhibitor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255959(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin-6-...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255960(4-(6-methylpyridin-2-yl)-5-(quinoxalin-6-yl)thiazo...)
Affinity DataKi:  0.330nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255959(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin-6-...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255228(N-(5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(5-flu...)
Affinity DataKi:  2.07nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255227(N-(5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(6-met...)
Affinity DataKi:  2.95nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255958(6-(4-(5-fluoro-6-methylpyridin-2-yl)-2-(4-(methyls...)
Affinity DataKi:  3nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255179(N-(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin...)
Affinity DataKi:  7.10nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255231(N-(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255230(N-(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255908(4-(5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(5-flu...)
Affinity DataKi:  15nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255957(1-(4-(5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(5-...)
Affinity DataKi:  15.2nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255909(6-(4-(5-fluoro-6-methylpyridin-2-yl)-2-(4-methylpi...)
Affinity DataKi:  16.4nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255906(N-(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin...)
Affinity DataKi:  19nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255907(6-(4-(5-fluoro-6-methylpyridin-2-yl)-2-(piperidin-...)
Affinity DataKi:  53.2nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255229(N-(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin...)
Affinity DataKi: >2.80E+4nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed