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Found
14
Enz. Inhib. hit(s) with all data for entry = 50028023
Target
Macrophage colony-stimulating factor 1 receptor
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50255518
(4-(3,4-dichlorophenylamino)-7-methoxy-6-(4-methylp...)
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Affinity Data
IC50: 2nM
Assay Description:
Inhibition of CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Macrophage colony-stimulating factor 1 receptor
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50255594
(4-(2,3-dichlorophenylamino)-7-fluoro-6-(4-methylpi...)
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Affinity Data
IC50: 3nM
Assay Description:
Inhibition of CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Macrophage colony-stimulating factor 1 receptor
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50255517
(4-(2,4-dichlorophenylamino)-7-methoxy-6-(4-methylp...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Inhibition of CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Macrophage colony-stimulating factor 1 receptor
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50255811
(4-(2,4-difluorophenylamino)-7-ethoxy-6-(4-methylpi...)
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Affinity Data
IC50: 6nM
Assay Description:
Inhibition of CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Macrophage colony-stimulating factor 1 receptor
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50255520
(4-(2,4-difluorophenylamino)-7-methoxy-6-(4-methylp...)
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Affinity Data
IC50: 6nM
Assay Description:
Inhibition of CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Macrophage colony-stimulating factor 1 receptor
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50255592
(4-(2,3-dichlorophenylamino)-6-(4-methylpiperazin-1...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8nM
Assay Description:
Inhibition of CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Macrophage colony-stimulating factor 1 receptor
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50255649
(4-(2,4-difluorophenylamino)-6-methoxy-7-(4-methylp...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Macrophage colony-stimulating factor 1 receptor
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50255648
(4-(2,3-dichlorophenylamino)-6-methoxy-7-(4-methylp...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
Assay Description:
Inhibition of CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Macrophage colony-stimulating factor 1 receptor
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50255647
(4-(3,4-dichlorophenylamino)-6-methoxy-7-(4-methylp...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 24nM
Assay Description:
Inhibition of CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Macrophage colony-stimulating factor 1 receptor
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50255418
(4-(2,4-difluorophenylamino)-6,7-dimethoxyquinoline...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 25nM
Assay Description:
Inhibition of CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Macrophage colony-stimulating factor 1 receptor
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50255646
(4-(2,4-difluorophenylamino)-7-fluoro-6-(4-methylpi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 54nM
Assay Description:
Inhibition of CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Macrophage colony-stimulating factor 1 receptor
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50255591
(4-(3,4-dichlorophenylamino)-6-(4-methylpiperazin-1...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 59nM
Assay Description:
Inhibition of CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Macrophage colony-stimulating factor 1 receptor
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50255593
(4-(2,4-difluorophenylamino)-6-(4-methylpiperazin-1...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 110nM
Assay Description:
Inhibition of CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Macrophage colony-stimulating factor 1 receptor
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50255590
(4-(2,4-dichlorophenylamino)-6-(4-methylpiperazin-1...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 129nM
Assay Description:
Inhibition of CSF1R
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL