Compile Data Set for Download or QSAR
Report error Found 129 Enz. Inhib. hit(s) with all data for entry = 50028019
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265774(4-Amino-3-benzimidazol-2-yl-5-(1-methyl(3-piperidy...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265746({4-Amino-3-[6-(4-methylpiperazinyl)benzimidazol-2-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265574(3-(1H-benzo[d]imidazol-2-yl)-4-(4-ethyl-1-methylpi...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265678(4-Amino-5-chloro-3-[6-(4-methylpiperazinyl)benzimi...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265773(4-Amino-3-benzimidazol-2-yl-5-(4-methylpiperazinyl...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265750(4-Amino-7-fluoro-3-[6-(4-methylpiperazinyl)benzimi...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265745(4-Amino-6-(benzylamino)-3-(6-(4-methylpiperazin-1-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265679(4-Amino-5-methyl-3-[6-(4-methylpiperazinyl)benzimi...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265641(4-Amino-3-{6-[(4-methylpiperazinyl)carbonyl]benzim...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265613(3-(1H-benzo[d]imidazol-2-yl)-4-(piperidin-4-ylmeth...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265774(4-Amino-3-benzimidazol-2-yl-5-(1-methyl(3-piperidy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265738(4-Amino-6-fluoro-3-[6-(4-methylpiperazinyl)benzimi...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265676(N-(2-(4-Amino-2-oxo-1,2-dihydroquinolin-3-yl)-1H-b...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265773(4-Amino-3-benzimidazol-2-yl-5-(4-methylpiperazinyl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265678(4-Amino-5-chloro-3-[6-(4-methylpiperazinyl)benzimi...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265675(4-Amino-3-(6-((4-methylpiperazin-1-yl)methyl)-1H-b...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50181320(4-amino-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]i...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265737(4-Amino-5-(methylamino)-3-(6-(4-methylpiperazin-1-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265679(4-Amino-5-methyl-3-[6-(4-methylpiperazinyl)benzimi...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265676(N-(2-(4-Amino-2-oxo-1,2-dihydroquinolin-3-yl)-1H-b...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265750(4-Amino-7-fluoro-3-[6-(4-methylpiperazinyl)benzimi...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of FGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265753(4-Amino-6,7-difluoro-3-(6-(4-methylpiperazin-1-yl)...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265639(3-{5-[(3S)-3-(Dimethylamino)pyrrolidinyl]benzimida...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265640(4-Amino-3-[5-(2-morpholin-4-ylethoxy)-benzimidazol...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265638(4-Amino-3-[6-(4-methyl(1,4-diazaperhydroepinyl))be...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265771(4-Amino-5,7-difluoro-3-[6-(4-methylpiperazinyl)ben...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265774(4-Amino-3-benzimidazol-2-yl-5-(1-methyl(3-piperidy...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50181311(4-amino-3-(6-morpholino-1H-benzo[d]imidazol-2-yl)q...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265740(4,6-Diamino-3-(6-(4-methylpiperazin-1-yl)-1H-benzo...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265743(4-Amino-6-(dimethylamino)-3-[6-(4-methylpiperaziny...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265740(4,6-Diamino-3-(6-(4-methylpiperazin-1-yl)-1H-benzo...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265745(4-Amino-6-(benzylamino)-3-(6-(4-methylpiperazin-1-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265739(4-Amino-6-chloro-3-[6-(4-methylpiperazinyl)benzimi...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265751(4-Amino-7-(methylamino)-3-[6-(4-methylpiperazinyl)...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50181320(4-amino-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]i...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265675(4-Amino-3-(6-((4-methylpiperazin-1-yl)methyl)-1H-b...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50181305(4-amino-3-(1H-benzo[d]imidazol-2-yl)quinolin-2(1H)...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265641(4-Amino-3-{6-[(4-methylpiperazinyl)carbonyl]benzim...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265746({4-Amino-3-[6-(4-methylpiperazinyl)benzimidazol-2-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265615(4-Amino-3-(5,6-dimethylbenzimidazol-2-yl)hydroquin...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265679(4-Amino-5-methyl-3-[6-(4-methylpiperazinyl)benzimi...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265678(4-Amino-5-chloro-3-[6-(4-methylpiperazinyl)benzimi...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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