Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50027891
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243945(N-cycloheptyl-6,7-dimethoxy-2-(4-(piperidin-1-yl)p...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244380(N-cycloheptyl-6,7-dimethoxy-2-(4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265669((1'-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquinaz...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265742({1'-[4-(Cycloheptylamino)-6,7-dimethoxyquinazolin-...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265669((1'-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquinaz...)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245036(N-(4-Chlorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265742({1'-[4-(Cycloheptylamino)-6,7-dimethoxyquinazolin-...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243945(N-cycloheptyl-6,7-dimethoxy-2-(4-(piperidin-1-yl)p...)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265667(1'-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquinazo...)
Affinity DataIC50: 48nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265670(N-(4-Chlorophenyl)-6,7-dimethoxy-2-[3-(methoxymeth...)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265669((1'-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquinaz...)
Affinity DataIC50: 58nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265749(1'-(4-{[2-(4-Chlorophenyl)ethyl]amino}-6,7-dimetho...)
Affinity DataIC50: 61nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265670(N-(4-Chlorophenyl)-6,7-dimethoxy-2-[3-(methoxymeth...)
Affinity DataIC50: 64nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265667(1'-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquinazo...)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265748((1'-{4-[(4-Chlorobenzyl)amino]-6,7-dimethoxyquinaz...)
Affinity DataIC50: 87nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265668(N-(4-chlorophenyl)-6,7-dimethoxy-2-(3-methoxy-1,4'...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265733([4-(1-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquin...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265742({1'-[4-(Cycloheptylamino)-6,7-dimethoxyquinazolin-...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245036(N-(4-Chlorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1...)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244380(N-cycloheptyl-6,7-dimethoxy-2-(4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245036(N-(4-Chlorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243945(N-cycloheptyl-6,7-dimethoxy-2-(4-(piperidin-1-yl)p...)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265748((1'-{4-[(4-Chlorobenzyl)amino]-6,7-dimethoxyquinaz...)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265760([1'-(4-{[3-(4-Chlorophenyl)propyl]amino}-6,7-dimet...)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244380(N-cycloheptyl-6,7-dimethoxy-2-(4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265670(N-(4-Chlorophenyl)-6,7-dimethoxy-2-[3-(methoxymeth...)
Affinity DataIC50: 230nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265749(1'-(4-{[2-(4-Chlorophenyl)ethyl]amino}-6,7-dimetho...)
Affinity DataIC50: 390nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265668(N-(4-chlorophenyl)-6,7-dimethoxy-2-(3-methoxy-1,4'...)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265667(1'-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquinazo...)
Affinity DataIC50: 430nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265748((1'-{4-[(4-Chlorobenzyl)amino]-6,7-dimethoxyquinaz...)
Affinity DataIC50: 450nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265668(N-(4-chlorophenyl)-6,7-dimethoxy-2-(3-methoxy-1,4'...)
Affinity DataIC50: 510nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265733([4-(1-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquin...)
Affinity DataIC50: 620nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50265761({1'-[4-(4-Chlorophenyl)-6,7-dimethoxyquinazolin-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed