Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50027854
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266148(N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266221(N-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]p...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266221(N-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]p...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266091(1-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]p...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266149(1-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266148(N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM14983(4-methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyri...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266187(N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266148(N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 19nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266148(N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Tie2 autophosphorylation in human Ea.hy926 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266118(N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 23nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266185(N-[4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266221(N-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]p...)
Affinity DataIC50: 28nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266187(N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 30nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266091(1-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]p...)
Affinity DataIC50: 34nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266149(1-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 40nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266188(N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 44nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266185(N-[4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-...)
Affinity DataIC50: 69nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266221(N-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]p...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266188(N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 88nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266150(7-methyl-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266186(1-methyl-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 240nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266186(1-methyl-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 250nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266118(N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266119(N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM14983(4-methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyri...)
Affinity DataIC50: 310nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266147(N-(2,3-dimethyl-4-(3-(2-(methylamino)pyrimidin-4-y...)
Affinity DataIC50: 310nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266117(1-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 460nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266092(N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 470nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266120(N-(2-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 590nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266148(N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266150(7-methyl-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266221(N-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]p...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266092(N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266117(1-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266147(N-(2,3-dimethyl-4-(3-(2-(methylamino)pyrimidin-4-y...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266120(N-(2-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266119(N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266118(N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed