Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50027843
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265989BDBM50265989(N-(3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)q...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266023BDBM50266023(N-(benzo[c][1,2,5]oxadiazol-4-ylmethyl)-3-(4-methy...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265954BDBM50265954(3-(4-methylpiperazin-1-yl)-N-(3-nitrobenzyl)-7-(tr...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265987BDBM50265987(3-(4-methylpiperazin-1-yl)-N-(4-nitrobenzyl)-7-(tr...)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265923BDBM50265923(5-(3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)q...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265988BDBM50265988(2-(4-methylpiperazin-1-yl)-8-(3-nitrobenzyloxy)-6-...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265924BDBM50265924(1-methyl-5-(3-(4-methylpiperazin-1-yl)-7-(trifluor...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266024BDBM50266024(N-(benzo[c][1,2,5]oxadiazol-5-ylmethyl)-3-(4-methy...)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265922BDBM50265922(5-(3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)q...)
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265955BDBM50265955(3-(4-methylpiperazin-1-yl)-N-(2-nitrobenzyl)-7-(tr...)
Affinity DataIC50: 540nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266255BDBM50266255(3-(4-methylpiperazin-1-yl)-5-phenyl-7-(trifluorome...)
Affinity DataIC50: 650nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265990BDBM50265990(3-((3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)...)
Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265839BDBM50265839(4-(3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)q...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265838BDBM50265838(3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)q...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265952BDBM50265952(N-benzyl-3-(4-methylpiperazin-1-yl)-7-(trifluorome...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266287BDBM50266287(1-(4-(8-phenyl-6-(trifluoromethyl)quinoxalin-2-yl)...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266254BDBM50266254(2-(4-methylpiperazin-1-yl)-8-phenyl-6-(trifluorome...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266329BDBM50266329(8-(3,4-dimethoxyphenyl)-2-(4-methylpiperazin-1-yl)...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266330BDBM50266330(8-(2,3-dichlorophenyl)-2-(4-methylpiperazin-1-yl)-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265925BDBM50265925(3-(4-methylpiperazin-1-yl)-N-phenyl-7-(trifluorome...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265866BDBM50265866(8-(1H-indol-6-yl)-2-(4-methylpiperazin-1-yl)-6-(tr...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266291BDBM50266291(6-chloro-2-(4-methylpiperazin-1-yl)-8-phenylquinox...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266290BDBM50266290(6-fluoro-2-(4-methylpiperazin-1-yl)-8-phenylquinox...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266327BDBM50266327(6-methyl-2-(4-methylpiperazin-1-yl)-8-phenylquinox...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265837BDBM50265837(3-(3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)q...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266257BDBM50266257(N,N-dimethyl-8-phenyl-6-(trifluoromethyl)quinoxali...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265953BDBM50265953(3-(4-methylpiperazin-1-yl)-N-phenethyl-7-(trifluor...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265840BDBM50265840(2-(4-methylpiperazin-1-yl)-8-(3-nitrophenyl)-6-(tr...)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266288BDBM50266288(2-(1-methylpiperidin-4-yloxy)-8-phenyl-6-(trifluor...)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266256BDBM50266256(8-phenyl-6-(trifluoromethyl)quinoxalin-2-amine | C...)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266289BDBM50266289(2-(4-methylpiperazin-1-yl)-8-phenylquinoxaline | C...)
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266328BDBM50266328(2-(4-methylpiperazin-1-yl)-8-phenylquinoxaline-6-c...)
Affinity DataIC50: 6.02E+4nMAssay Description:Inhibition of human recombinant his-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed