Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 2971
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26497(N-[5-({6-[4-(dimethylamino)phenyl]pyrimidin-4-yl}a...)
Affinity DataIC50: 1.50E+4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26486(N-{2-chloro-5-[(6-phenylpyrimidin-4-yl)amino]pheny...)
Affinity DataIC50: 1.60E+4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26499(N-(2-methyl-5-{[6-(4-phenylphenyl)pyrimidin-4-yl]a...)
Affinity DataIC50: 1.90E+4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26501(N-(5-{[6-(2,3-dihydro-1,4-benzodioxin-6-yl)pyrimid...)
Affinity DataIC50: 2.10E+4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26484(N-{2-methyl-5-[(6-phenylpyrimidin-4-yl)amino]pheny...)
Affinity DataIC50: 2.40E+4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26487(N-{2-bromo-5-[(6-phenylpyrimidin-4-yl)amino]phenyl...)
Affinity DataIC50: 3.00E+4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26500(N-[5-({6-[4-(3-hydroxypropyl)phenyl]pyrimidin-4-yl...)
Affinity DataIC50: 3.70E+4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26489(N-{2-methoxy-5-[(6-phenylpyrimidin-4-yl)amino]phen...)
Affinity DataIC50: 6.90E+4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26488(N-{2-fluoro-5-[(6-phenylpyrimidin-4-yl)amino]pheny...)
Affinity DataIC50: 1.10E+5nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26498(N-(2-methyl-5-{[6-(2-methylphenyl)pyrimidin-4-yl]a...)
Affinity DataIC50: 2.19E+5nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26496(N-[5-({6-[2-(dimethylamino)phenyl]pyrimidin-4-yl}a...)
Affinity DataIC50: 3.17E+5nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26485(N-{3-[(6-phenylpyrimidin-4-yl)amino]phenyl}methane...)
Affinity DataIC50: 4.00E+5nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26491(N-{5-[(6-phenylpyrimidin-4-yl)amino]-2-(prop-2-en-...)
Affinity DataIC50: 5.70E+5nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26494(N-{2-methyl-5-[(6-phenylpyrimidin-4-yl)amino]pheny...)
Affinity DataIC50: 6.00E+5nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26493(4-bromo-1-N-(6-phenylpyrimidin-4-yl)benzene-1,3-di...)
Affinity DataIC50: 6.00E+5nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26492(N-(4-bromo-3-nitrophenyl)-6-phenylpyrimidin-4-amin...)
Affinity DataIC50: 6.00E+5nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26490(N-{2-phenyl-5-[(6-phenylpyrimidin-4-yl)amino]pheny...)
Affinity DataIC50: 6.00E+5nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26495(N-methyl-N-{2-methyl-5-[(6-phenylpyrimidin-4-yl)am...)
Affinity DataIC50: 1.60E+6nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed