Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50032134
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US9133148, A | US11753371, Compound...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant FAAH expressed in Cos7 cells after 30 mins by using anandamide as a substrate by LC-MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US9133148, A | US11753371, Compound...)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant MAGL expressed in Cos7 cells after 30 mins by using 2-AG as a substrate by LC-MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US9133148, A | US11753371, Compound...)
Affinity DataIC50: 8nMAssay Description:Inhibition of MAGL in C57B1/6J mouse brain membrane after 30 mins by using 2-AG as a substrate by LC-MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US9133148, A | US11753371, Compound...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of FAAH in C57B1/6J mouse brain membrane after 20 mins by using oleamide as a substrate by LC-MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50128581(cyclohexyl biphenyl-3-ylcarbamate | CHEMBL77767 | ...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MAGL in Wistar rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed