Compile Data Set for Download or QSAR
Report error Found 116 Enz. Inhib. hit(s) with all data for entry = 50027688
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254766(2-(3-(2,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254687(N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(naphth...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254841(2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at human EP3 receptor assessed as cAMP production by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254883(N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(4-meth...)
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254728(N-(4-methoxyphenylsulfonyl)-2-(3-(naphthalen-2-ylt...)
Affinity DataIC50: 0.700nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254520(N-(3,4-difluorophenylsulfonyl)-2-(3-(naphthalen-2-...)
Affinity DataIC50: 0.700nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254647(2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human EP3 receptor assessed as cAMP production by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254841(2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254640(N-(2,5-dimethoxyphenylsulfonyl)-2-(3-(naphthalen-2...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254768(N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(2,4-di...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254841(2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254641(N-(2-chlorophenylsulfonyl)-2-(3-(naphthalen-2-ylth...)
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254880(N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(3,4-di...)
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255058(N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(naphth...)
Affinity DataIC50: 1.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254797(2-(3-(2-chloro-4-fluorophenylthio)-1H-indol-4-ylox...)
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254767(N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(2,4-di...)
Affinity DataIC50: 1.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254520(N-(3,4-difluorophenylsulfonyl)-2-(3-(naphthalen-2-...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254686(N-(3-chlorophenylsulfonyl)-2-(3-(naphthalen-2-ylth...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254647(2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254686(N-(3-chlorophenylsulfonyl)-2-(3-(naphthalen-2-ylth...)
Affinity DataIC50: 2.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254730(2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)-N-(ph...)
Affinity DataIC50: 2.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254643(N-(3,5-dichlorophenylsulfonyl)-2-(3-(naphthalen-2-...)
Affinity DataIC50: 2.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254924(N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(1-meth...)
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254797(2-(3-(2-chloro-4-fluorophenylthio)-1H-indol-4-ylox...)
Affinity DataIC50: 2.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254838(N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(pyridi...)
Affinity DataIC50: 2.80nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254473(4,5-Dichlorothiophene-2-sulfonic Acid[2-(3-Naphtha...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254642(2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)-N-(th...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254882(2-(3-(4-chlorophenylthio)-1H-indol-4-yloxy)-N-(4,5...)
Affinity DataIC50: 3.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254729(N-(5-chlorothiophen-2-ylsulfonyl)-2-(3-(naphthalen...)
Affinity DataIC50: 3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254643(N-(3,5-dichlorophenylsulfonyl)-2-(3-(naphthalen-2-...)
Affinity DataIC50: 3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254881(2-(3-(4-(2-amino-2-oxoethyl)phenylthio)-1H-indol-4...)
Affinity DataIC50: 3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254964(N-(3,4-difluorophenylsulfonyl)-2-(3-(naphthalen-2-...)
Affinity DataIC50: 3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254647(2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...)
Affinity DataIC50: 3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254839(N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(quinol...)
Affinity DataIC50: 3.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255026(N-(3,5-difluorophenylsulfonyl)-2-(3-(naphthalen-2-...)
Affinity DataIC50: 3.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254882(2-(3-(4-chlorophenylthio)-1H-indol-4-yloxy)-N-(4,5...)
Affinity DataIC50: 4.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254684(N-(3,5-difluorophenylsulfonyl)-2-(3-(naphthalen-2-...)
Affinity DataIC50: 4.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254729(N-(5-chlorothiophen-2-ylsulfonyl)-2-(3-(naphthalen...)
Affinity DataIC50: 4.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254839(N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(quinol...)
Affinity DataIC50: 4.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254647(2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...)
Affinity DataIC50: 4.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254689(2-(3-(4-(2-amino-2-oxoethyl)phenylsulfonyl)-1H-ind...)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254768(N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(2,4-di...)
Affinity DataIC50: 5.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254923(N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(phenyl...)
Affinity DataIC50: 5.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255092(2-(3-(2,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...)
Affinity DataIC50: 5.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254684(N-(3,5-difluorophenylsulfonyl)-2-(3-(naphthalen-2-...)
Affinity DataIC50: 5.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255094(N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(2,4-di...)
Affinity DataIC50: 5.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254798(2-(3-(2-chlorophenylthio)-1H-indol-4-yloxy)-N-(4,5...)
Affinity DataIC50: 5.80nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255028(N-(3-chlorophenylsulfonyl)-2-(3-(naphthalen-2-ylsu...)
Affinity DataIC50: 5.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254475(N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(2,5-di...)
Affinity DataIC50: 6.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254476(2-(3-(benzo[d]thiazol-2-ylsulfonyl)-1H-indol-4-ylo...)
Affinity DataIC50: 7.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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