Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50027673
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254720((4-(7-butyl-9-(morpholinosulfonyl)-3,9-diazaspiro[...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254677((4-(7-butyl-9-(pyridin-2-ylsulfonyl)-3,9-diazaspir...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254752(1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254675((4-(7-butyl-9-(phenylsulfonyl)-3,9-diazaspiro[5.5]...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254748((R)-(4-(7-butyl-9-(2,2,2-trifluoroethylsulfonyl)-3...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254716((4-(7-butyl-9-(cyclopropylsulfonyl)-3,9-diazaspiro...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254718((4-(7-butyl-9-(tetrahydro-2H-pyran-4-ylsulfonyl)-3...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254715((4-(7-butyl-9-(methylsulfonyl)-3,9-diazaspiro[5.5]...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254719((4-(7-butyl-9-(1-methyl-1H-imidazol-4-ylsulfonyl)-...)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254751(7-butyl-3-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254750(1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254756(5-(4-(7-butyl-9-((1-hydroxypiperidin-4-yl)methyl)-...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254676((R)-1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbony...)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254749(1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4...)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254717(1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4...)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254754(methyl 4-((1-butyl-9-(1-(4,6-dimethylpyrimidine-5-...)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254722(4-(1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl...)
Affinity DataIC50: 64nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254755(1-butyl-3-((1-(2,2-difluoroethyl)piperidin-4-yl)me...)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254753(1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4...)
Affinity DataIC50: 76nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254721(1-(4-(1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbo...)
Affinity DataIC50: 78nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254757((4-(9-(cyclopropylsulfonyl)-7-propoxy-3,9-diazaspi...)
Affinity DataIC50: 80nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254787((4,6-dimethylpyrimidin-5-yl)(4-methyl-4-(9-(methyl...)
Affinity DataIC50: 104nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254672(5-(4-(7-butyl-9-(tetrahydro-2H-pyran-4-carbonyl)-3...)
Affinity DataIC50: 217nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254673(tetrahydro-2H-pyran-4-yl 1-butyl-9-(1-(4,6-dimethy...)
Affinity DataIC50: 349nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254674((4-(7-butyl-9-((tetrahydro-2H-pyran-4-yl)methyl)-3...)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254671((1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-...)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254750(1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CCR1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254750(1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CCR2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254750(1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254750(1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CCR4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254750(1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CCR6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254750(1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CXCR4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed