Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50027651
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(CHEMBL505914 | CHEMBL518571 | 1-(6-(((S)-3-(4-fluo...)
Affinity DataIC50: 0.120nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(CHEMBL505914 | CHEMBL518571 | 1-(6-(((S)-3-(4-fluo...)
Affinity DataIC50: 0.150nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255006(1-((5R,6S)-6-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50: 0.230nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231358(1-{(1R,2S)-3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-...)
Affinity DataIC50: 0.300nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255042(1-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl...)
Affinity DataIC50: 0.370nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255042(1-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl...)
Affinity DataIC50: 0.370nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254448(1-(6-((ethyl(3-(4-fluorophenyl) propyl)amino)methy...)
Affinity DataIC50: 0.470nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254448(1-(6-((ethyl(3-(4-fluorophenyl) propyl)amino)methy...)
Affinity DataIC50: 0.470nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255070(1-(5-acetyl-4-methylthiazol-2-yl)-3-(6-(((S)-3-(4-...)
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50209984(1-(5-acetyl-4-methylthiazol-2-yl)-3-((3S,4S)-4-(((...)
Affinity DataIC50: 1.20nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50163634(1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-...)
Affinity DataIC50: 2nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255038(1-((5R,6S)-6-((cyclopropyl(3-(4-fluorophenyl)propy...)
Affinity DataIC50: 2.10nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255042(1-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl...)
Affinity DataIC50: 5.40nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254447(1-(4-tert-butylthiazol-2-yl)-3-(6-(((S)-3-(4-fluor...)
Affinity DataIC50: 5.5nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254447(1-(4-tert-butylthiazol-2-yl)-3-(6-(((S)-3-(4-fluor...)
Affinity DataIC50: 5.5nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255039(1-((5R,6S)-6-(((3-(4-fluorophenyl)propyl)(propyl)a...)
Affinity DataIC50: 9.20nMAssay Description:Binding affinity to CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50163634(1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255042(1-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255006(1-((5R,6S)-6-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254448(1-(6-((ethyl(3-(4-fluorophenyl) propyl)amino)methy...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254448(1-(6-((ethyl(3-(4-fluorophenyl) propyl)amino)methy...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50209984(1-(5-acetyl-4-methylthiazol-2-yl)-3-((3S,4S)-4-(((...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(CHEMBL505914 | CHEMBL518571 | 1-(6-(((S)-3-(4-fluo...)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of human ERG by calcium-flux based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(CHEMBL505914 | CHEMBL518571 | 1-(6-(((S)-3-(4-fluo...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255070(1-(5-acetyl-4-methylthiazol-2-yl)-3-(6-(((S)-3-(4-...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(CHEMBL505914 | CHEMBL518571 | 1-(6-(((S)-3-(4-fluo...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254447(1-(4-tert-butylthiazol-2-yl)-3-(6-(((S)-3-(4-fluor...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231358(1-{(1R,2S)-3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed