Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50027562
TargetHydroxycarboxylic acid receptor 3(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208137(5-(5-bromothiophen-3-yl)-5-methyl-4-oxo-4,5-dihydr...)
Affinity DataEC50:  1.47E+3nMAssay Description:Activity at GPR109b assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 3(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208122(5-(5-chlorothiophen-3-yl)-5-methyl-4-oxo-4,5-dihyd...)
Affinity DataEC50:  1.72E+3nMAssay Description:Activity at GPR109b assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241028(1-Isopropyl-1H-benzotriazole-5-carboxylic acid | 1...)
Affinity DataEC50:  400nMAssay Description:Activity at GPR109a assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208137(5-(5-bromothiophen-3-yl)-5-methyl-4-oxo-4,5-dihydr...)
Affinity DataEC50:  110nMAssay Description:Activity at GPR109a assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208122(5-(5-chlorothiophen-3-yl)-5-methyl-4-oxo-4,5-dihyd...)
Affinity DataEC50:  200nMAssay Description:Activity at GPR109a assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208138((+)-acifran | 5-Methyl-4-oxo-5-phenyl-4,5-dihydro-...)
Affinity DataIC50: 500nMAssay Description:Activity at GPR109a assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208138((+)-acifran | 5-Methyl-4-oxo-5-phenyl-4,5-dihydro-...)
Affinity DataIC50: 500nMAssay Description:Activity at GPR109a assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 3(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208138((+)-acifran | 5-Methyl-4-oxo-5-phenyl-4,5-dihydro-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Activity at GPR109b assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50216551(5-butylpyrazole-3-carboxylic acid | 5-pentyl-1H-py...)
Affinity DataKi:  72nMAssay Description:Binding affinity at GPR109aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132140(1,4,5,6-Tetrahydro-cyclopentapyrazole-3-carboxylic...)
Affinity DataKi:  156nMAssay Description:Binding affinity at GPR109aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132142(4,5,6,7-Tetrahydro-1H-indazole-3-carboxylic acid |...)
Affinity DataKi:  3.50E+3nMAssay Description:Binding affinity at GPR109aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed