Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50027541
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273882(2-[3-chloro-3-phenylprop-2-enylidene]hydrazinecarb...)
Affinity DataIC50: 900nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273849(1-Chloro-5,7-dimethyl-3,4-dihydronaphthalene-2-car...)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273851(2-[(3-chloro-1H-inden-2-yl)methylene]hydrazinecarb...)
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253469(2-[(1-chloro-3,4-dihydronaphthalen-2-yl)methylene]...)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273883(beta-Chloro-alpha-methylcinnamaldehyde guanylhydra...)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273850(1-Chloro-3-dihydro-4-methylnaphthalene-2-carboxald...)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273848(1-Chloro-6-methoxy-3,4-dihydronaphthalene-2-carbox...)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp70(MMTV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273848(1-Chloro-6-methoxy-3,4-dihydronaphthalene-2-carbox...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp70(MMTV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273849(1-Chloro-5,7-dimethyl-3,4-dihydronaphthalene-2-car...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp70(MMTV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273883(beta-Chloro-alpha-methylcinnamaldehyde guanylhydra...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273854(1-Methoxy-3,4-dihydronaphthalene-2-carboxaldehyde ...)
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273852(9-Chloro-6,7-dihydro-5-benzocycloheptene-8-carboxa...)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273880(1-Phenoxy-3,4-dihydronaphthalene-2-carboxaldehyde ...)
Affinity DataIC50: 3.50E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp160(MVV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273852(9-Chloro-6,7-dihydro-5-benzocycloheptene-8-carboxa...)
Affinity DataIC50: 3.60E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 100 nM estradiol-induced transcriptional activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp70(MMTV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253469(2-[(1-chloro-3,4-dihydronaphthalen-2-yl)methylene]...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp70(MMTV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273847(1-Chloro-7-methoxy-3,4-dihydronaphthalene-2-carbox...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273847(1-Chloro-7-methoxy-3,4-dihydronaphthalene-2-carbox...)
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp70(MMTV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273852(9-Chloro-6,7-dihydro-5-benzocycloheptene-8-carboxa...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp70(MMTV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273882(2-[3-chloro-3-phenylprop-2-enylidene]hydrazinecarb...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp70(MMTV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273853(1-Bromo-3,4-dihydronaphthalene-2-carboxaldehyde gu...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp70(MMTV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273880(1-Phenoxy-3,4-dihydronaphthalene-2-carboxaldehyde ...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp70(MMTV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273851(2-[(3-chloro-1H-inden-2-yl)methylene]hydrazinecarb...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50240439(2-(1-Naphthalenylmethylene) hydrazinecarboximidami...)
Affinity DataIC50: 7.50E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50240438(N''-[(1E)-2-naphthylmethylene]carbonohydrazonic di...)
Affinity DataIC50: 7.50E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273853(1-Bromo-3,4-dihydronaphthalene-2-carboxaldehyde gu...)
Affinity DataIC50: 7.80E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp70(MMTV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273850(1-Chloro-3-dihydro-4-methylnaphthalene-2-carboxald...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253469(2-[(1-chloro-3,4-dihydronaphthalen-2-yl)methylene]...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC binding to recombinant estrogen receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp70(MMTV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50240438(N''-[(1E)-2-naphthylmethylene]carbonohydrazonic di...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp70(MMTV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50240439(2-(1-Naphthalenylmethylene) hydrazinecarboximidami...)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273881(1-(1,1,1,-Trifluoromethyl)-3,4-dihydronaphthalene-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273852(9-Chloro-6,7-dihydro-5-benzocycloheptene-8-carboxa...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC binding to recombinant estrogen receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273883(beta-Chloro-alpha-methylcinnamaldehyde guanylhydra...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC binding to recombinant estrogen receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp160(HIV-1)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253469(2-[(1-chloro-3,4-dihydronaphthalen-2-yl)methylene]...)
Affinity DataIC50: 2.50E+7nMAssay Description:Displacement of [3H]estradiol from human estrogen receptor alpha/estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed