Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 4976
TargetLysosomal acid glucosylceramidase(Human)
Research Institute, Hospital For Sick Children

LigandPNGBDBM84610(5-(3,5-dichlorophenoxy)-N-(4-pyrdinyl)-2- furamide...)
Affinity DataIC50: 4.70E+3nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2012
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Research Institute, Hospital For Sick Children

LigandPNGBDBM18046(CHEMBL83547 | 5-((4-methylphenyl)thio)-quinazoline...)
Affinity DataIC50: 7.80E+3nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2012
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Research Institute, Hospital For Sick Children

LigandPNGBDBM84609(7,8-diethoxy-quinazoline 2,4-diamine, 1b)
Affinity DataIC50: 2.20E+4nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2012
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Research Institute, Hospital For Sick Children

LigandPNGBDBM84608(2,4-diamino-6-nitro-quinazoline, 1a)
Affinity DataIC50: 6.10E+4nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2012
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Research Institute, Hospital For Sick Children

LigandPNGBDBM84611(2-methyl-N-pyridin-4-yl-benzamide, 2a)
Affinity DataIC50: 8.00E+4nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2012
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Research Institute, Hospital For Sick Children

LigandPNGBDBM84612(2,2-dimethyl-N-(4-pyridinyl)propanamide, 2b)
Affinity DataIC50: 4.00E+5nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2012
Entry Details Article
PubMed