Compile Data Set for Download or QSAR
Report error Found 111 Enz. Inhib. hit(s) with all data for entry = 50027519
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274953(5-(3-benzylpyrrolidin-3-yl)-1H-indole-2-carbonitri...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274951(5-(3-benzylpyrrolidin-3-yl)-1-methyl-1H-indole | C...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274949(5-(3-(3-methoxybenzyl)pyrrolidin-3-yl)-1H-indole |...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274921(5-(3-(4-fluorobenzyl)pyrrolidin-3-yl)-1H-indole | ...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274950(5-(3-phenethylpyrrolidin-3-yl)-1H-indole | CHEMBL5...)
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275438(CHEMBL487355 | (+)-5-(3-benzylpyrrolidin-3-yl)-1H-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275439(5-(3-benzylpyrrolidin-3-yl)-1H-indazole | CHEMBL52...)
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274952(ethyl 5-(3-benzylpyrrolidin-3-yl)-1H-indole-2-carb...)
Affinity DataIC50: 600nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274976(5-(3-benzylpyrrolidin-3-yl)-1H-indole-3-carbonitri...)
Affinity DataIC50: 800nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((-)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (+)-6-...)
Affinity DataIC50: 900nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275378(3-(1H-indol-3-yl)-N-methyl-3-phenylpropan-1-amine ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274953(5-(3-benzylpyrrolidin-3-yl)-1H-indole-2-carbonitri...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((-)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (+)-6-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((-)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (+)-6-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274919(3-(3-benzylpyrrolidin-3-yl)-1H-indole | CHEMBL5144...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274975(5-(3-benzylpyrrolidin-3-yl)-N,N-dimethyl-1H-indole...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275378(3-(1H-indol-3-yl)-N-methyl-3-phenylpropan-1-amine ...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275438(CHEMBL487355 | (+)-5-(3-benzylpyrrolidin-3-yl)-1H-...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275438(CHEMBL487355 | (+)-5-(3-benzylpyrrolidin-3-yl)-1H-...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274979(5-(3-butylpyrrolidin-3-yl)-1H-indole | CHEMBL46358...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274920(5-(3-(pyridin-2-ylmethyl)pyrrolidin-3-yl)-1H-indol...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274954(5-(3-benzylpyrrolidin-3-yl)-1H-indole-2-carboxamid...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274979(5-(3-butylpyrrolidin-3-yl)-1H-indole | CHEMBL46358...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274974(5-(3-benzylpyrrolidin-3-yl)-N-methyl-1H-indole-2-c...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274951(5-(3-benzylpyrrolidin-3-yl)-1-methyl-1H-indole | C...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274978(5-(3-propylpyrrolidin-3-yl)-1H-indole | CHEMBL4633...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274977(5-(3-methylpyrrolidin-3-yl)-1H-indole | CHEMBL4633...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274921(5-(3-(4-fluorobenzyl)pyrrolidin-3-yl)-1H-indole | ...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275438(CHEMBL487355 | (+)-5-(3-benzylpyrrolidin-3-yl)-1H-...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274974(5-(3-benzylpyrrolidin-3-yl)-N-methyl-1H-indole-2-c...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274954(5-(3-benzylpyrrolidin-3-yl)-1H-indole-2-carboxamid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275440(3-(benzo[b]thiophen-5-yl)-3-benzylpyrrolidine | CH...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275441(5-(3-benzylpyrrolidin-3-yl)-1H-pyrrolo[2,3-b]pyrid...)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274920(5-(3-(pyridin-2-ylmethyl)pyrrolidin-3-yl)-1H-indol...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274953(5-(3-benzylpyrrolidin-3-yl)-1H-indole-2-carbonitri...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275439(5-(3-benzylpyrrolidin-3-yl)-1H-indazole | CHEMBL52...)
Affinity DataKi:  1nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274951(5-(3-benzylpyrrolidin-3-yl)-1-methyl-1H-indole | C...)
Affinity DataKi:  1nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274954(5-(3-benzylpyrrolidin-3-yl)-1H-indole-2-carboxamid...)
Affinity DataKi:  2nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275440(3-(benzo[b]thiophen-5-yl)-3-benzylpyrrolidine | CH...)
Affinity DataKi:  3nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274952(ethyl 5-(3-benzylpyrrolidin-3-yl)-1H-indole-2-carb...)
Affinity DataKi:  4nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274951(5-(3-benzylpyrrolidin-3-yl)-1-methyl-1H-indole | C...)
Affinity DataKi:  4nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275439(5-(3-benzylpyrrolidin-3-yl)-1H-indazole | CHEMBL52...)
Affinity DataKi:  5nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274976(5-(3-benzylpyrrolidin-3-yl)-1H-indole-3-carbonitri...)
Affinity DataKi:  5nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275438(CHEMBL487355 | (+)-5-(3-benzylpyrrolidin-3-yl)-1H-...)
Affinity DataKi:  6nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274921(5-(3-(4-fluorobenzyl)pyrrolidin-3-yl)-1H-indole | ...)
Affinity DataKi:  7nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275440(3-(benzo[b]thiophen-5-yl)-3-benzylpyrrolidine | CH...)
Affinity DataKi:  7nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274920(5-(3-(pyridin-2-ylmethyl)pyrrolidin-3-yl)-1H-indol...)
Affinity DataKi:  8nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((-)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (+)-6-...)
Affinity DataKi:  8nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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