Compile Data Set for Download or QSAR
Report error Found 84 Enz. Inhib. hit(s) with all data for entry = 50030218
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292637((-)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'...)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292638((-)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperid...)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292638((-)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperid...)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: 80nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: 80nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292637((-)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'...)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292637((-)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'...)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292665((+/-)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperi...)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292665((+/-)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperi...)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292667((+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin...)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292648((+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiper...)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292670((+/-)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperi...)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292673((+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin...)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292672((+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin...)
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292669((+/-)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperi...)
Affinity DataIC50: 290nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292657((+/-)-3-(3-aminophenyl)-1'-(4-bromobenzyl)-3,4'-bi...)
Affinity DataIC50: 320nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292666((+/-)-ethyl 1'-(4-bromobenzyl)-3-phenyl-3,4'-bipip...)
Affinity DataIC50: 320nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018553(CHEMBL10309 | (+/-)-1'-(4-bromobenzyl)-3-phenyl-3,...)
Affinity DataIC50: 330nMAssay Description:Displacement of [125I]ITAC from CXCR3 in PHA/IL-2 activated human PBMC pretreated 30 mins before [125I]ITAC challenge after 1 hr by liquid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)
Affinity DataIC50: 330nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292640((-)-1'-(4-chloro-3-fluorobenzyl)-3-phenyl-3,4'-bip...)
Affinity DataIC50: 340nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292674((+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin...)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292642((+/-)-1'-(4-bromobenzyl)-3-(pyridin-2-yl)-3,4'-bip...)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018553(CHEMBL10309 | (+/-)-1'-(4-bromobenzyl)-3-phenyl-3,...)
Affinity DataIC50: 610nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292644((+/-)-1'-(4-bromobenzyl)-3-(pyridin-4-yl)-3,4'-bip...)
Affinity DataIC50: 630nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292651((+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiper...)
Affinity DataIC50: 630nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292668((+/-)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperi...)
Affinity DataIC50: 690nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018553(CHEMBL10309 | (+/-)-1'-(4-bromobenzyl)-3-phenyl-3,...)
Affinity DataIC50: 780nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018553(CHEMBL10309 | (+/-)-1'-(4-bromobenzyl)-3-phenyl-3,...)
Affinity DataIC50: 780nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292655((+/-)-1'-(4-bromobenzyl)-3-(3-(morpholine-4-carbon...)
Affinity DataIC50: 790nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: 810nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018560(1'-(4-Chloro-benzyl)-3-phenyl-[3,4']bipiperidinyl-...)
Affinity DataIC50: 830nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292664((+/-)-1'-(4-bromobenzyl)-1-(methylthiomethyl)-3-ph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292658((+/-)-1'-(4-bromobenzyl)-3-(3-hydroxyphenyl)-3,4'-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292643((+/-)-1'-(4-bromobenzyl)-3-(pyridin-3-yl)-3,4'-bip...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292639((+/-)-1'-(3,4-dichlorobenzyl)-3-phenyl-3,4'-bipipe...)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292645((+/-)-1'-(4-bromobenzyl)-3-(4-fluorophenyl)-3,4'-b...)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292656((+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiper...)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292654((+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiper...)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292649((+/-)-1'-(4-bromobenzyl)-3-(3-chlorophenyl)-3,4'-b...)
Affinity DataIC50: 1.45E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292647((+/-)-1'-(4-bromobenzyl)-3-(3-methoxyphenyl)-3,4'-...)
Affinity DataIC50: 1.55E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292676((+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin...)
Affinity DataIC50: 1.58E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292663((+/-)-1'-(4-bromobenzyl)-1-(2-methoxyethyl)-3-phen...)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292665((+/-)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperi...)
Affinity DataIC50: 2.31E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292677((+/-)-1'-(4-methylbenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292660((+/-)-1'-(4-bromobenzyl)-1-ethyl-3-phenyl-3,4'-bip...)
Affinity DataIC50: 2.51E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292659((+/-)-1'-(4-bromobenzyl)-1-methyl-3-phenyl-3,4'-bi...)
Affinity DataIC50: 2.51E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292641((+/-)-1'-(4-chloro-3-(trifluoromethyl)benzyl)-3-ph...)
Affinity DataIC50: 2.51E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292665((+/-)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperi...)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292679((+/-)-1'-(2,4-dichlorobenzyl)-3-phenyl-3,4'-bipipe...)
Affinity DataIC50: 3.16E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
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