Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 2935
TargetTyrosine-protein kinase JAK3(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM26198(Jak Inhibitor 1 | CHEMBL21156 | Compound # 2 | 4-t...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit JAK3 RTK activity. The compounds were incubated with enzyme, 10 uM ATP, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2008
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM26199(N-[4-(4-methylpiperazin-1-yl)phenyl]-3-phenyl-1H-p...)
Affinity DataIC50: 98nMpH: 7.5 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit JAK3 RTK activity. The compounds were incubated with enzyme, 10 uM ATP, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2008
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16018(cid_8515 | SP 600125 | ChemBiol10705 Compound 4 | ...)
Affinity DataIC50: 957nMpH: 7.5 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit JAK3 RTK activity. The compounds were incubated with enzyme, 10 uM ATP, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2008
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM26200(N-(1H-indazol-5-yl)-5-methyl-1-[3-(trifluoromethyl...)
Affinity DataIC50: 2.64E+3nMpH: 7.5 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit JAK3 RTK activity. The compounds were incubated with enzyme, 10 uM ATP, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2008
Entry Details Article
PubMed