Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50038736
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50264117(3-[1-(4-Hydroxy-2-methoxy-phenyl)-meth-(E)-ylidene...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at human cloned wild-type alpha7 nAChR expressed in Xenopus laevis oocytes assessed as channel opening by voltage clamp electrophysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50093255(2'H-spiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxaz...)
Affinity DataEC50:  3.60E+3nMAssay Description:Agonist activity at human cloned wild-type alpha7 nAChR expressed in Xenopus laevis oocytes assessed as channel opening by voltage clamp electrophysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50093255(2'H-spiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxaz...)
Affinity DataKd:  92nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50264117(3-[1-(4-Hydroxy-2-methoxy-phenyl)-meth-(E)-ylidene...)
Affinity DataKd:  23nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50061564(3-[1-(2,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-3,4,...)
Affinity DataKd:  158nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50093259(3'-Ethylspiro[1-azabicyclo[2.2.2]octane-3,5'-oxazo...)
Affinity DataKd:  690nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50093253(3'-Methylspiro[1-azabicyclo[2.2.2]octane-3,5'-oxaz...)
Affinity DataKd:  220nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed