Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50027313
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275692(N-(1-(3-methoxypropyl)-5-((phenylamino)methyl)-1H-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275651(N-(5-((cyclohexyl(methyl)amino)methyl)-1-(3-methox...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM26813(N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoyleth...)
Affinity DataIC50: 12nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275615(3-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 20nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275654(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 27nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275653(N-(1-(3-(1H-imidazol-1-yl)propyl)-5-((cyclohexyl(m...)
Affinity DataIC50: 30nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275556(4-cyano-N-(5-(((cyclopentylmethyl)(methyl)amino)me...)
Affinity DataIC50: 34nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275618(N-(5-((cyclohexyl(methyl)amino)methyl)-1-(3-methox...)
Affinity DataIC50: 36nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275652(N-(1-(3-amino-3-oxopropyl)-5-((cyclohexyl(methyl)a...)
Affinity DataIC50: 41nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275554(4-cyano-N-(5-((cyclohexylamino)methyl)-1-(3-methox...)
Affinity DataIC50: 45nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275587(4-chloro-N-(5-((cyclohexyl(methyl)amino)methyl)-1-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275690(N-(1-(3-(1H-imidazol-1-yl)propyl)-5-((cyclohexyl(m...)
Affinity DataIC50: 46nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 46nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275617(N-(5-((cyclohexyl(methyl)amino)methyl)-1-(3-methox...)
Affinity DataIC50: 47nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275555(4-cyano-N-(1-(3-methoxypropyl)-5-((phenylamino)met...)
Affinity DataIC50: 48nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275691(N-(5-((cyclohexylamino)methyl)-1-(3-methoxypropyl)...)
Affinity DataIC50: 53nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275585(4-cyano-N-(1-(3-methoxypropyl)-5-(morpholinomethyl...)
Affinity DataIC50: 69nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275584(4-cyano-N-(5-((2-methoxyethylamino)methyl)-1-(3-me...)
Affinity DataIC50: 81nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275741(4-cyano-N-(1-(3-methoxypropyl)-5-(((1-methylpiperi...)
Affinity DataIC50: 110nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275553(4-cyano-N-(1-(3-methoxypropyl)-5-((methylamino)met...)
Affinity DataIC50: 170nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275616(3-bromo-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275586(N-(5-((cyclohexyl(methyl)amino)methyl)-1-(3-methox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed