Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50027279
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253229(Isosorbide-2-(benzylcarbamate)-5-mononitrate | CHE...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human plasma BuchE after 60 mins by carbamylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253231(Isosorbide-2-(benzylcarbamate)-5-benzoate | (3R,3a...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252786(Isosorbide-2-benzylcarbamate-5-cyclopentanoate | C...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253266((3R,3aR,6S,6aR)-6-(benzylcarbamoyloxy)hexahydrofur...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253264(2-(Benzylaminocarbonyloxy-)-5-O-(1-naphthoyl)-1,4:...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253265(2-(Benzylaminocarbonyloxy-)-5-O-(2-naphthoyl)-1,4:...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253229(Isosorbide-2-(benzylcarbamate)-5-mononitrate | CHE...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253230((3R,3aR,6S,6aR)-6-(benzylcarbamoyloxy)hexahydrofur...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM10624(CHEMBL140020 | CHEMBL464538 | 1,5-bis(4-allyldimet...)
Affinity DataIC50: 63nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252789(Isosorbide-2-(butylcarbamate)-5-benzoate | CHEMBL4...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252745(2-(Benzylaminocarbonyloxy-) 5-(coumarincarbonyloxy...)
Affinity DataIC50: 73nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253263(Isosorbide-2-benzylcarbamate-5-isonicotinate | CHE...)
Affinity DataIC50: 88nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 103nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252743(2-(Benzylaminocarbonyloxy-) 5-O-cinnamoyl-1,4:3,6-...)
Affinity DataIC50: 137nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252785(Isosorbide-2-benzylcarbamate-5-cyclopropanoate | C...)
Affinity DataIC50: 334nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252787(Isosorbide-2-benzylcarbamate-5-triflate | CHEMBL49...)
Affinity DataIC50: 359nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253226(Isosorbide-2-(propylcarbamate)-5-mononitrate | CHE...)
Affinity DataIC50: 639nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252788(Isosorbide-2-(methylcarbamate)-5-benzoate | CHEMBL...)
Affinity DataIC50: 669nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252784(Isosorbide-2-benzylcarbamate-5-pentanoate | CHEMBL...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50: 733nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253227(Isosorbide-2-(butylcarbamate)-5-mononitrate | CHEM...)
Affinity DataIC50: 894nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252783(Isosorbide-2-benzylcarbamate-5-propionate | CHEMBL...)
Affinity DataIC50: 980nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253228(Isosorbide-2-(cyclohexylcarbamate)-5-mononitrate |...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252744(Isosorbide-2-benzylcarbamate-5-(p-heptyloxybenzoat...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252790(isosorbide-2-benzyl carbamate | Isosorbide-2-benzy...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253225(Isosorbide-2-(ethylcarbamate)-5-mononitrate | CHEM...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252742(Isosorbide-2-benzylcarbamate-5-acetate | CHEMBL493...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253156(Isosorbide-2-(methylcarbamate)-5-mononitrate | CHE...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252741(Isosorbide-2-(3,4-dichlorophenylcarbamate)-5-monon...)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253156(Isosorbide-2-(methylcarbamate)-5-mononitrate | CHE...)
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253264(2-(Benzylaminocarbonyloxy-)-5-O-(1-naphthoyl)-1,4:...)
Affinity DataIC50: 3.76E+4nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253265(2-(Benzylaminocarbonyloxy-)-5-O-(2-naphthoyl)-1,4:...)
Affinity DataIC50: 4.34E+4nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253266((3R,3aR,6S,6aR)-6-(benzylcarbamoyloxy)hexahydrofur...)
Affinity DataIC50: 5.16E+4nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252743(2-(Benzylaminocarbonyloxy-) 5-O-cinnamoyl-1,4:3,6-...)
Affinity DataIC50: 5.59E+4nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252786(Isosorbide-2-benzylcarbamate-5-cyclopentanoate | C...)
Affinity DataIC50: 5.63E+4nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252745(2-(Benzylaminocarbonyloxy-) 5-(coumarincarbonyloxy...)
Affinity DataIC50: 6.04E+4nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253231(Isosorbide-2-(benzylcarbamate)-5-benzoate | (3R,3a...)
Affinity DataIC50: 2.21E+5nMAssay Description:Inhibition of human erythrocyte AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM10624(CHEMBL140020 | CHEMBL464538 | 1,5-bis(4-allyldimet...)
Affinity DataIC50: 2.55E+5nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253231(Isosorbide-2-(benzylcarbamate)-5-benzoate | (3R,3a...)
Affinity DataIC50: 2.73E+5nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253226(Isosorbide-2-(propylcarbamate)-5-mononitrate | CHE...)
Affinity DataIC50: 1.52E+6nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253227(Isosorbide-2-(butylcarbamate)-5-mononitrate | CHEM...)
Affinity DataIC50: 1.44E+6nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed