Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50027215
TargetMu-type opioid receptor(Guinea pig)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252861(H-D-Phe-c[Cys-Tyr-DTrp-Orn-Thr-Pen]-Thr-NH2 | CHEM...)
Affinity DataIC50: 2.80nMAssay Description:Antagonist activity against mu opioid receptor in guinea pig ileum assessed as effect on TAPP-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252861(H-D-Phe-c[Cys-Tyr-DTrp-Orn-Thr-Pen]-Thr-NH2 | CHEM...)
Affinity DataIC50: 1.35E+4nMAssay Description:Antagonist activity against delta opioid receptor in mouse vas deference assessed as effect on DPDPE-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252860((S)-N-((S)-1,6-diamino-1-oxohexan-2-yl)-1-((S)-5-g...)
Affinity DataKi:  0.823nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252855((4S,7S,13S)-13-[(S)-3-(4-Carbamoyl-2,6-dimethyl-ph...)
Affinity DataKi:  1.02nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252864(antanal 2 | CHEMBL454035)
Affinity DataKi:  1.52nMAssay Description:Antagonist activity against mu opioid receptor in guinea pig ileum assessed as effect on TAPP-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252856((4S,7S,13S)-13-[(S)-3-(4-Hydroxy-2,6-dimethyl-phen...)
Affinity DataKi:  2.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252858((S)-2-({(4R,7S,13S)-7-(4-Fluoro-benzyl)-13-[(S)-3-...)
Affinity DataKi:  2.32nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252863(antanal 1 | CHEMBL507442)
Affinity DataKi:  2.38nMAssay Description:Antagonist activity against mu opioid receptor in guinea pig ileum assessed as effect on TAPP-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252857((S)-2-{[(4R,7S,13S)-13-[(S)-3-(4-Carbamoyl-2,6-dim...)
Affinity DataKi:  2.92nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252856((4S,7S,13S)-13-[(S)-3-(4-Hydroxy-2,6-dimethyl-phen...)
Affinity DataKi:  3.61nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252864(antanal 2 | CHEMBL454035)
Affinity DataKi:  7.74nMAssay Description:Antagonist activity against delta opioid receptor in mouse vas deference assessed as effect on DPDPE-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252862((5S,8S,14R)-8-Benzyl-14-[(S)-2-[3-(4-hydroxy-2,6-d...)
Affinity DataKi:  15.5nMAssay Description:Antagonist activity against mu opioid receptor in guinea pig ileum assessed as effect on TAPP-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252863(antanal 1 | CHEMBL507442)
Affinity DataKi:  17.4nMAssay Description:Antagonist activity against delta opioid receptor in mouse vas deference assessed as effect on DPDPE-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252855((4S,7S,13S)-13-[(S)-3-(4-Carbamoyl-2,6-dimethyl-ph...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252859((S)-1-((S)-2-((2S,3S)-2-((S)-2-((S)-2-((S)-2-((S)-...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252859((S)-1-((S)-2-((2S,3S)-2-((S)-2-((S)-2-((S)-2-((S)-...)
Affinity DataKi:  27.2nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252859((S)-1-((S)-2-((2S,3S)-2-((S)-2-((S)-2-((S)-2-((S)-...)
Affinity DataKi:  29.6nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252856((4S,7S,13S)-13-[(S)-3-(4-Hydroxy-2,6-dimethyl-phen...)
Affinity DataKi:  92.8nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252860((S)-N-((S)-1,6-diamino-1-oxohexan-2-yl)-1-((S)-5-g...)
Affinity DataKi:  163nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252855((4S,7S,13S)-13-[(S)-3-(4-Carbamoyl-2,6-dimethyl-ph...)
Affinity DataKi:  185nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252860((S)-N-((S)-1,6-diamino-1-oxohexan-2-yl)-1-((S)-5-g...)
Affinity DataKi:  213nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252862((5S,8S,14R)-8-Benzyl-14-[(S)-2-[3-(4-hydroxy-2,6-d...)
Affinity DataKi:  273nMAssay Description:Antagonist activity against delta opioid receptor in mouse vas deference assessed as effect on DPDPE-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252858((S)-2-({(4R,7S,13S)-7-(4-Fluoro-benzyl)-13-[(S)-3-...)
Affinity DataKi:  406nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252857((S)-2-{[(4R,7S,13S)-13-[(S)-3-(4-Carbamoyl-2,6-dim...)
Affinity DataKi:  3.65E+3nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252858((S)-2-({(4R,7S,13S)-7-(4-Fluoro-benzyl)-13-[(S)-3-...)
Affinity DataKi:  3.71E+3nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50252857((S)-2-{[(4R,7S,13S)-13-[(S)-3-(4-Carbamoyl-2,6-dim...)
Affinity DataKi:  5.85E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed