Compile Data Set for Download or QSAR
Report error Found 80 Enz. Inhib. hit(s) with all data for entry = 50027213
Target5-hydroxytryptamine receptor 7(Guinea pig)
Università

Curated by ChEMBL
LigandPNGBDBM50253208(N-Benzyl-4-(2-diphenyl)-1-piperazinehexanamide | C...)
Affinity DataEC50:  4.50E+6nMAssay Description:Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Guinea pig)
Università

Curated by ChEMBL
LigandPNGBDBM50253130(2-[6-[4-(2-Diphenyl)-1-piperazinyl]-1-oxohexyl]-1,...)
Affinity DataEC50:  490nMAssay Description:Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Guinea pig)
Università

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataEC50:  630nMAssay Description:Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Guinea pig)
Università

Curated by ChEMBL
LigandPNGBDBM50253244(4-(2-Diphenyl)-N-(4-pyridinylmethyl)-1-piperazineh...)
Affinity DataEC50:  310nMAssay Description:Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Guinea pig)
Università

Curated by ChEMBL
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataEC50:  600nMAssay Description:Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253208(N-Benzyl-4-(2-diphenyl)-1-piperazinehexanamide | C...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253244(4-(2-Diphenyl)-N-(4-pyridinylmethyl)-1-piperazineh...)
Affinity DataKi:  0.980nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253062(2-[6-[4-(2-Methylthiophenyl)-1-piperazinyl]-1-oxoh...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253131(2-[6-[4-(2-(1-Methylethyl)phenyl)-1-piperazinyl]-1...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253089(2-[6-[4-(2-Methylthiophenyl)-1-piperazinyl]-1-oxoh...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM21393(cid_1220 | CHEMBL56 | 7-(dipropylamino)-5,6,7,8-te...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253088(2-[6-[4-(2-Methoxyphenyl)-1-piperazinyl]-1-oxohexy...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253131(2-[6-[4-(2-(1-Methylethyl)phenyl)-1-piperazinyl]-1...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253130(2-[6-[4-(2-Diphenyl)-1-piperazinyl]-1-oxohexyl]-1,...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253245(4-[2-(1-Methylethyl)phenyl]-N-(4-pyridinylmethyl)-...)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253247(N-(4-Cyanophenylmethyl)-4-(2-methylthiophenyl)-1-p...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50252691(N-(4-Methanesulfonyloxyphenylmethyl)-4-(2-diphenyl...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253131(2-[6-[4-(2-(1-Methylethyl)phenyl)-1-piperazinyl]-1...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50252692(N-(4-Methanesulfonyloxyphenylmethyl)-4-[2-(1-methy...)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253211(4-(2-Methylthiophenyl)-N-(4-pyridinylmethyl)-1-pip...)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253086(2-[6-[4-(2-Diphenyl)-1-piperazinyl]-1-oxohexyl]iso...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253282(N-(4-Cyanophenylmethyl)-4-[2-(1-methylethyl)phenyl...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253247(N-(4-Cyanophenylmethyl)-4-(2-methylthiophenyl)-1-p...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253209(N-Benzyl-4-[2-(1-methylethyl)phenyl]-1-piperazineh...)
Affinity DataKi:  9.20nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253284(N-(4-Methanesulfonyloxyphenylmethyl)-4-(2-methylth...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253133(N-Benzyl-4-(2-methylthiophenyl)-1-piperazinehexana...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253210(N-Benzyl-4-(2-methoxyphenyl)-1-piperazinehexanamid...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253246(4-(2-Methoxyphenyl)-N-(4-pyridinylmethyl)-1-pipera...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253282(N-(4-Cyanophenylmethyl)-4-[2-(1-methylethyl)phenyl...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253245(4-[2-(1-Methylethyl)phenyl]-N-(4-pyridinylmethyl)-...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253132(2-[6-[4-(2-Methoxyphenyl)-1-piperazinyl]-1-oxohexy...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253133(N-Benzyl-4-(2-methylthiophenyl)-1-piperazinehexana...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253087(2-[6-[4-(2-(1-Methylethyl)phenyl)-1-piperazinyl]-1...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50252693(N-(4-Methanesulfonyloxyphenylmethyl)-4-(2-methoxyp...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253284(N-(4-Methanesulfonyloxyphenylmethyl)-4-(2-methylth...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253132(2-[6-[4-(2-Methoxyphenyl)-1-piperazinyl]-1-oxohexy...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253133(N-Benzyl-4-(2-methylthiophenyl)-1-piperazinehexana...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253089(2-[6-[4-(2-Methylthiophenyl)-1-piperazinyl]-1-oxoh...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253211(4-(2-Methylthiophenyl)-N-(4-pyridinylmethyl)-1-pip...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253132(2-[6-[4-(2-Methoxyphenyl)-1-piperazinyl]-1-oxohexy...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253089(2-[6-[4-(2-Methylthiophenyl)-1-piperazinyl]-1-oxoh...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253062(2-[6-[4-(2-Methylthiophenyl)-1-piperazinyl]-1-oxoh...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253283(N-(4-Cyanophenylmethyl)-4-(2-methoxyphenyl)-1-pipe...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253282(N-(4-Cyanophenylmethyl)-4-[2-(1-methylethyl)phenyl...)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253087(2-[6-[4-(2-(1-Methylethyl)phenyl)-1-piperazinyl]-1...)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50252692(N-(4-Methanesulfonyloxyphenylmethyl)-4-[2-(1-methy...)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50253211(4-(2-Methylthiophenyl)-N-(4-pyridinylmethyl)-1-pip...)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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