Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50032132
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50228363(N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...)
Affinity DataEC50:  160nMAssay Description:Activation of human SirT2 protein fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant G9aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50216689(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of SirT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of Histone H3 lysine 9 of GLP methyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed