Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50027188
TargetSodium-dependent serotonin transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50073436(CHEMBL114275 | CHEMBL2314219 | (2-(2-((dimethylami...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]IPT from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50264817(N-(5-chloro-2-(2-((dimethylamino)methyl)phenylthio...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]IDAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-methyl-...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]MADAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-methyl-...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]paroxetine from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50264818(N-(5-bromo-2-(2-((dimethylamino)methyl)phenylthio)...)
Affinity DataKi:  8nMAssay Description:Displacement of [125I]IDAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265295(N,N-Dimethyl-2-[2-(N-4-fluorobenzylamine)-4-tolylt...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]MADAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265291(N,N-Dimethyl-2-[2-(N-4-fluorobenzamide)-4-tolylthi...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]MADAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50264816(N-(2-(2-((dimethylamino)methyl)phenylthio)phenyl)-...)
Affinity DataKi:  34nMAssay Description:Displacement of [125I]IDAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265294(N,N-Dimethyl-2-[2-(N-4-nitrobenzylamine)-4-tolylth...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]MADAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265293(N-Methyl-2-[2-(N-4-fluorobenzylamine)-4-tolylthio]...)
Affinity DataKi: >100nMAssay Description:Displacement of [3H]MADAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265292(N,N-Dimethyl-2-[2-(N-4-nitrobenzamide)-4-tolylthio...)
Affinity DataKi: >100nMAssay Description:Displacement of [3H]MADAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50264819(N-(2-(2-((dimethylamino)methyl)phenylthio)-5-iodop...)
Affinity DataKi:  193nMAssay Description:Displacement of [125I]IDAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-methyl-...)
Affinity DataKi:  325nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50264820(N-Methyl-2-[2-(N-4-fluorobenzamide)-4-tolylthio]be...)
Affinity DataKi: >500nMAssay Description:Displacement of [3H]MADAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265292(N,N-Dimethyl-2-[2-(N-4-nitrobenzamide)-4-tolylthio...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265293(N-Methyl-2-[2-(N-4-fluorobenzylamine)-4-tolylthio]...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265294(N,N-Dimethyl-2-[2-(N-4-nitrobenzylamine)-4-tolylth...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GBR-12935 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265292(N,N-Dimethyl-2-[2-(N-4-nitrobenzamide)-4-tolylthio...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GBR-12935 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265291(N,N-Dimethyl-2-[2-(N-4-fluorobenzamide)-4-tolylthi...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GBR-12935 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50264820(N-Methyl-2-[2-(N-4-fluorobenzamide)-4-tolylthio]be...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GBR-12935 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-methyl-...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GBR-12935 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265295(N,N-Dimethyl-2-[2-(N-4-fluorobenzylamine)-4-tolylt...)
Affinity DataKi: >1.20E+3nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265295(N,N-Dimethyl-2-[2-(N-4-fluorobenzylamine)-4-tolylt...)
Affinity DataKi: >1.50E+3nMAssay Description:Displacement of [3H]GBR-12935 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265294(N,N-Dimethyl-2-[2-(N-4-nitrobenzylamine)-4-tolylth...)
Affinity DataKi: >1.90E+3nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265293(N-Methyl-2-[2-(N-4-fluorobenzylamine)-4-tolylthio]...)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [3H]GBR-12935 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50264820(N-Methyl-2-[2-(N-4-fluorobenzamide)-4-tolylthio]be...)
Affinity DataKi: >2.50E+3nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50265291(N,N-Dimethyl-2-[2-(N-4-fluorobenzamide)-4-tolylthi...)
Affinity DataKi: >5.20E+3nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed