Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50027131
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264878(cis-4-{[2-({4-[(1E)-3-morpholin-4-yl-3-oxoprop-1-e...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264880((trans)-4-((2-(4-((E)-3-morpholino-3-oxoprop-1-eny...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265320((trans)-4-(2-(4-((E)-3-morpholino-3-oxoprop-1-enyl...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265147((E)-1-morpholino-3-(4-(2-(piperidin-4-yloxy)phenyl...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265190((E)-1-morpholino-3-(4-(3-(tetrahydro-2H-thiopyran-...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265149((E)-1-morpholino-3-(4-(2-(tetrahydro-2H-pyran-4-yl...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264778(4-{(2E)-3-[4-{[2-(pyridin-3-ylmethoxy)phenyl]sulfa...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265286((cis)-4-(3-(4-((E)-3-morpholino-3-oxoprop-1-enyl)-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264881((trans)-4-((3-(4-((E)-3-morpholino-3-oxoprop-1-eny...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264879((cis)-4-((3-(4-((E)-3-morpholino-3-oxoprop-1-enyl)...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264876((E)-1-morpholino-3-(4-(2-(pyridin-4-ylmethoxy)phen...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265148((E)-1-morpholino-3-(4-(3-(piperidin-4-yloxy)phenyl...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265285((cis)-4-(2-(4-((E)-3-morpholino-3-oxoprop-1-enyl)-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265106((E)-3-(4-(2-(cyclohexyloxy)phenylthio)-2,3-bis(tri...)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265322((E)-3-(4-(2-((1H-imidazol-4-yl)methoxy)phenylthio)...)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264753((E)-1-morpholino-3-(4-(2-(pyridin-2-ylmethoxy)phen...)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265366((E)-1-morpholino-3-(4-(2-(thiophen-2-ylmethoxy)phe...)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265321((trans)-4-(3-(4-((E)-3-morpholino-3-oxoprop-1-enyl...)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265246((E)-3-(4-(2-((cis)-4-methylcyclohexyloxy)phenylthi...)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265367((E)-3-(4-(2-(benzyloxy)phenylthio)-2,3-bis(trifluo...)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265188((E)-1-morpholino-3-(4-(3-(tetrahydro-2H-pyran-4-yl...)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265248((E)-3-(4-(2-((trans)-4-methylcyclohexyloxy)phenylt...)
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264877((E)-1-morpholino-3-(4-(3-(pyridin-4-ylmethoxy)phen...)
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265189((E)-1-morpholino-3-(4-(2-(tetrahydro-2H-thiopyran-...)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265365((E)-3-(4-(3-((1H-imidazol-4-yl)methoxy)phenylthio)...)
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264875((E)-1-morpholino-3-(4-(3-(pyridin-3-ylmethoxy)phen...)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264754((E)-1-morpholino-3-(4-(3-(pyridin-2-ylmethoxy)phen...)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264752((E)-3-(4-(3-(benzyloxy)phenylthio)-2,3-bis(trifluo...)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265107((E)-3-(4-(3-(cyclohexyloxy)phenylthio)-2,3-bis(tri...)
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265284((E)-3-(4-(3-((trans)-4-methylcyclohexyloxy)phenylt...)
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265247((E)-3-(4-(3-((cis)-4-methylcyclohexyloxy)phenylthi...)
Affinity DataIC50: 860nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed