Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 2869
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25553(4-[(2,4-dichlorophenyl)amino]-5-(3,4-dimethoxyphen...)
Affinity DataIC50: 80nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25554(5-(3,4-dimethoxyphenyl)-4-[(2,4-dimethylphenyl)ami...)
Affinity DataIC50: 160nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25551(5-(3,4-dimethoxyphenyl)-4-[(4-methoxyphenyl)amino]...)
Affinity DataIC50: 400nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25555(4-[(2,5-dichlorophenyl)amino]-5-(3,4-dimethoxyphen...)
Affinity DataIC50: 470nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25550(5-(3,4-dimethoxyphenyl)-4-[(4-methylphenyl)amino]p...)
Affinity DataIC50: 900nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25546(5-(3,4-dimethoxyphenyl)-4-[(3-fluorophenyl)amino]p...)
Affinity DataIC50: 1.40E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25544(5-(3,4-dimethoxyphenyl)-4-(phenylamino)pyridine-3-...)
Affinity DataIC50: 1.60E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25560(4-(2,3-dihydro-1H-inden-5-ylamino)-5-(3,4-dimethox...)
Affinity DataIC50: 2.00E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25557(5-(3,4-dimethoxyphenyl)-4-[(3,4-dimethoxyphenyl)am...)
Affinity DataIC50: 2.20E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25559(CHEMBL492252 | 5-(3,4-dimethoxyphenyl)-4-(1H-indol...)
Affinity DataIC50: 2.20E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25556(4-[(3,4-dichlorophenyl)amino]-5-(3,4-dimethoxyphen...)
Affinity DataIC50: 2.40E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25549(4-[(4-chlorophenyl)amino]-5-(3,4-dimethoxyphenyl)p...)
Affinity DataIC50: 2.80E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25545(4-[(3-chlorophenyl)amino]-5-(3,4-dimethoxyphenyl)p...)
Affinity DataIC50: 3.90E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25552(5-(3,4-dimethoxyphenyl)-4-[(4-phenoxyphenyl)amino]...)
Affinity DataIC50: 8.40E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25548(4-{[3-(benzyloxy)phenyl]amino}-5-(3,4-dimethoxyphe...)
Affinity DataIC50: 3.00E+4nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25547(5-(3,4-dimethoxyphenyl)-4-[(3-phenoxyphenyl)amino]...)
Affinity DataIC50: 3.00E+4nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25558(CHEMBL492251 | 5-(3,4-dimethoxyphenyl)-4-(1H-indol...)
Affinity DataKi:  79nM ΔG°:  -40.1kJ/mole IC50: 70nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25543(4-[(3-bromophenyl)amino]-5-(3,4-dimethoxyphenyl)py...)
Affinity DataKi:  4.90E+3nM ΔG°:  -30.0kJ/mole IC50: 4.60E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed