Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50027112
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263757((E)-3-(4-(3-(1-isopropylpiperidin-4-ylamino)phenyl...)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263657((cis)-4-(3-(4-((E)-3-morpholino-3-oxoprop-1-enyl)-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263755((E)-3-(4-(3-(1-methylpiperidin-4-ylamino)phenylthi...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263805((E)-1-morpholino-3-(4-(3-(1-propylpiperidin-4-ylam...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263806((E)-3-(4-(3-(8-methyl-8-azabicyclo[3.2.1]octan-3-y...)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263756((E)-3-(4-(3-(1-ethylpiperidin-4-ylamino)phenylthio...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263711((E)-1-morpholino-3-(4-(3-(piperidin-4-ylamino)phen...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263710((trans)-4-((3-(4-((E)-3-morpholino-3-oxoprop-1-eny...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263548((E)-3-(4-(3-aminophenylthio)-2,3-bis(trifluorometh...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263656((trans)-4-(3-(4-((E)-3-morpholino-3-oxoprop-1-enyl...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263709((cis)-4-((3-(4-((E)-3-morpholino-3-oxoprop-1-enyl)...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263596((E)-3-(4-(3-(methylamino)phenylthio)-2,3-bis(trifl...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263708((E)-1-morpholino-3-(4-(3-(tetrahydro-2H-pyran-4-yl...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263707((E)-3-{4-[3-(1-Methylene-1-oxo-hexahydro-1lambda*6...)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263807((E)-3-(4-(3-(1-acetylpiperidin-4-ylamino)phenylthi...)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263655((E)-3-(4-(3-(cyclobutylamino)phenylthio)-2,3-bis(t...)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263597((E)-3-(4-(3-(dimethylamino)phenylthio)-2,3-bis(tri...)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263598((E)-3-(4-(3-(cyclohexylamino)phenylthio)-2,3-bis(t...)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263658((cis/trans)-(E)-ethyl 4-(3-(4-(3-morpholino-3-oxop...)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263599((E)-3-(4-(3-(cyclopentylamino)phenylthio)-2,3-bis(...)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed