Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50027033
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253937(2-[4-(2-Bromo-5-thienyl)phenyl]-4-methyl-octahydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253939(2-[4-(2-Benzothiazolyl)phenyl]-4-methylmorpholin-2...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253493(3-[4-(4-Bromophenyl)phenyl]-octahydro-1,4-pyrido[2...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253492(2-[4-(4-Bromophenyl)phenyl]-4-methyl-octahydro-1,4...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253314(2-[4-(2-Benzothiazolyl)phenyl]-octahydro-1,4-pyrid...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253901(2-[4-(2-Thienyl)phenyl]-4-methylmorpholin-2-ol | C...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253940(2-[4-(2-Benzothiazolyl)phenyl]-4-methyl-octahydro-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253491(2-[4-(4-Bromophenyl)phenyl]-4-methyl-morphonyl-2-o...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253935(3-[4-(2-Thienyl)phenyl]-octahydro-1,4-pyrido[2,1-c...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253938(3-[4-(2-Bromo-5-thienyl)phenyl]-octahydro-1,4-pyri...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253319(2-[4-(4-Chlorophenyl)phenyl]-4-methyl-octahydro-1,...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253318(2-[4-(4-Chlorophenyl)phenyl]-4-methyl-morphonyl-2-...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253902(2-[4-(2-Thienyl)phenyl]-4-methyl-octahydro-1,4-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253496(3-[4-(4-Fluorophenyl)phenyl]-octahydro-1,4-pyrido[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253317(3-[4-(2-Fluorophenyl)phenyl]-octahydro-1,4-pyrido[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253936(2-[4-(2-Bromo-5-thienyl)phenyl]-4-methylmorpholin-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253359(3-[4-(4-Chlorophenyl)phenyl]-octahydro-1,4-pyrido[...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253494(2-[4-(4-Fluorophenyl)phenyl]-4-methyl-morphonyl-2-...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253495(2-[4-(4-Fluorophenyl)phenyl]-4-methyl-octahydro-1,...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50213690(2-Biphenyl-4-yl-4-methyl-octahydro-benzo[1,4]oxazi...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253315(2-[4-(2-Fluorophenyl)phenyl]-4-methyl-morphonyl-2-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50253316(2-[4-(2-Fluorophenyl)phenyl]-4-methyl-octahydro-1,...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsome measured by conversion of [3H]FPP to squaleneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed