Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50027004
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264262(3-(4-isopropylphenyl)-7-methyl-N-(2-(p-tolyloxy)et...)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264672(3-(4-isopropylphenyl)-7-methyl-N-(2-phenoxyethyl)p...)
Affinity DataEC50:  6.00E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264706(3-(4-isopropylphenyl)-7-methyl-N-(2-(naphthalen-2-...)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264707(3-(4-isopropylphenyl)-N-(2-(4-methoxyphenoxy)ethyl...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264133(3-(4-isopropylphenyl)-N-(2-(3-methoxyphenoxy)ethyl...)
Affinity DataEC50:  930nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264134(N-(2-(2-fluorophenoxy)ethyl)-3-(4-isopropylphenyl)...)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264135(N-(2-(4-fluorophenoxy)ethyl)-3-(4-isopropylphenyl)...)
Affinity DataEC50:  460nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264136(N-(2-(4-chlorophenoxy)ethyl)-3-(4-isopropylphenyl)...)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264187(3-(4-isopropylphenyl)-7-methyl-N-(2-(m-tolyloxy)et...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264263(rac-3-(4-isopropylphenyl)-7-methyl-N-(1-phenoxypro...)
Affinity DataEC50:  700nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264264((R)-3-(4-isopropylphenyl)-7-methyl-N-(1-phenoxypro...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264265((S)-3-(4-isopropylphenyl)-7-methyl-N-(1-phenoxypro...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264293(rac-3-(4-isopropylphenyl)-N-(2-methoxy-1-phenyleth...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264294(rac-3-(4-isopropylphenyl)-N-(1-methoxy-3-phenylpro...)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264671(rac-3-(4-isopropylphenyl)-N-(1-methoxypropan-2-yl)...)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264264((R)-3-(4-isopropylphenyl)-7-methyl-N-(1-phenoxypro...)
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264672(3-(4-isopropylphenyl)-7-methyl-N-(2-phenoxyethyl)p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264263(rac-3-(4-isopropylphenyl)-7-methyl-N-(1-phenoxypro...)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264265((S)-3-(4-isopropylphenyl)-7-methyl-N-(1-phenoxypro...)
Affinity DataIC50: 3.30E+3nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264671(rac-3-(4-isopropylphenyl)-N-(1-methoxypropan-2-yl)...)
Affinity DataIC50: 3.40E+3nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed