Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50026850
LigandChemical structure of BindingDB Monomer ID 50245169BDBM50245169(1-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245422BDBM50245422(6-(6,7-dimethoxyquinolin-4-yloxy)-N-(2-methoxyphen...)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245420BDBM50245420(N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245771BDBM50245771(1-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245421BDBM50245421(6-(6,7-dimethoxyquinolin-4-yloxy)-N-phenylnaphthal...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245418BDBM50245418(N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245419BDBM50245419(N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245378BDBM50245378(4-chloro-N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-me...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245770BDBM50245770(1-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245377BDBM50245377(3-chloro-N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-me...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245375BDBM50245375(N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245376BDBM50245376(N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245336BDBM50245336(4-chloro-N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-me...)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245769BDBM50245769(1-(2-chloro-4-(trifluoromethyl)phenyl)-3-(6-(6,7-d...)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245335BDBM50245335(2-chloro-N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-me...)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245420BDBM50245420(N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 45nMAssay Description:Inhibition of aurora 1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245333BDBM50245333(N-benzyl-6-(6,7-dimethoxyquinolin-4-yloxy)-1-methy...)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245294BDBM50245294(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-N-(4-(t...)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245420BDBM50245420(N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 121nMAssay Description:Inhibition of Tie 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245293BDBM50245293(6-(6,7-dimethoxyquinolin-4-yloxy)-N-(4-methoxyphen...)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245292BDBM50245292(6-(6,7-dimethoxyquinolin-4-yloxy)-N-(3-methoxyphen...)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245291BDBM50245291(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-N-pheny...)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245334BDBM50245334(N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 344nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245171BDBM50245171(6-(6,7-dimethoxyquinolin-4-yloxy)-N-ethyl-1-methyl...)
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245420BDBM50245420(N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 764nMAssay Description:Inhibition of aurora 2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245222BDBM50245222(N-butyl-6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl...)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245172BDBM50245172(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-N-propy...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245420BDBM50245420(N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245170BDBM50245170(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-inda...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50245420BDBM50245420(N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 3.25E+3nMAssay Description:Inhibition of PI3KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245420BDBM50245420(N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 3.32E+3nMAssay Description:Inhibition of cMETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245420BDBM50245420(N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 2.50E+7nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245420BDBM50245420(N-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-i...)
Affinity DataIC50: 2.50E+7nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed