Compile Data Set for Download or QSAR
Report error Found 93 Enz. Inhib. hit(s) with all data for entry = 50026848
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245511(3-amino-N-((R)-1-(4-(2-(1-amino-3-methylbutyl)phen...)
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human MC4 receptor expressed in cells assessed as inhibition of alpha-MSH-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245765(N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-hydroxy-3...)
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human MC4 receptor expressed in cells assessed as inhibition of alpha-MSH-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245484(3-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-h...)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human MC4 receptor expressed in cells assessed as inhibition of alpha-MSH-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245166((R)-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-hydroxype...)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at human MC4 receptor expressed in cells assessed as inhibition of alpha-MSH-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245486(N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-hydroxy-3...)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at human MC4 receptor expressed in cells assessed as inhibition of alpha-MSH-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245413((R)-3-amino-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-m...)
Affinity DataIC50: 650nMAssay Description:Antagonist activity at human MC4 receptor expressed in cells assessed as inhibition of alpha-MSH-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245535(N-((R)-1-(4-(2-(1-amino-3-methylbutyl)phenyl)piper...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50158484(3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245371((2R)-1-(4-(2-(1-amino-3-methylbutyl)phenyl)piperaz...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245534(2-amino-N-((R)-1-(4-(2-(1-amino-3-methylbutyl)phen...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245511(3-amino-N-((R)-1-(4-(2-(1-amino-3-methylbutyl)phen...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245536((S)-2-amino-N-((R)-1-(4-(2-(1-amino-3-methylbutyl)...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245563(N-((R)-1-(4-(2-(1-amino-3-methylbutyl)phenyl)piper...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245331((1S,2S)-ethyl 2-(4-((R)-2-(3-aminopropanamido)-3-(...)
Affinity DataKi:  6.30nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245537(2-amino-N-((R)-1-(4-(2-(1-amino-3-methylbutyl)phen...)
Affinity DataKi:  7.70nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245484(3-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-h...)
Affinity DataKi:  8.10nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245486(N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-hydroxy-3...)
Affinity DataKi:  8.30nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245722(2-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-((R)...)
Affinity DataKi:  9nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245166((R)-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-hydroxype...)
Affinity DataKi:  9.40nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245765(N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-hydroxy-3...)
Affinity DataKi:  9.60nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245719(3-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(2-h...)
Affinity DataKi:  11nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245720((R)-3-amino-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-h...)
Affinity DataKi:  11nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152808(4-(2R)-[(3R)-1,2,3,4-tetrahydroisoquinolinylcarbox...)
Affinity DataKi:  11nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245485(2-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-h...)
Affinity DataKi:  13nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245165((R)-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-hydroxype...)
Affinity DataKi:  13nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245368((2R)-1-(4-(2-(1-amino-3-methylbutyl)phenyl)piperaz...)
Affinity DataKi:  15nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245508((S)-2-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-...)
Affinity DataKi:  16nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245167((S)-2-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-...)
Affinity DataKi:  18nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245367((2R)-1-(4-(2-(1-amino-3-methylbutyl)phenyl)piperaz...)
Affinity DataKi:  21nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245510(N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-hydroxy-3...)
Affinity DataKi:  21nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245677(3-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-h...)
Affinity DataKi:  23nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245413((R)-3-amino-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-m...)
Affinity DataKi:  24nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245767((R)-2-amino-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-h...)
Affinity DataKi:  26nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245565(3-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-h...)
Affinity DataKi:  26nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245449((S)-2-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-...)
Affinity DataKi:  26nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245764(2-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-((S)...)
Affinity DataKi:  28nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245605(3-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-h...)
Affinity DataKi:  29nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245448((R)-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-methylbut...)
Affinity DataKi:  31nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245676(3-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-h...)
Affinity DataKi:  32nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245447((R)-2-amino-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-m...)
Affinity DataKi:  33nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245221((R)-2-amino-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-h...)
Affinity DataKi:  38nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245288((R)-1-cyclopropyl-3-(3-(2,4-dichlorophenyl)-1-(4-(...)
Affinity DataKi:  42nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245509(2-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-h...)
Affinity DataKi:  46nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245606(3-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-h...)
Affinity DataKi:  47nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245766(N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-hydroxy-3...)
Affinity DataKi:  49nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245330((2R)-1-(4-(2-(1-amino-3-methylbutyl)phenyl)piperaz...)
Affinity DataKi:  53nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245607(3-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-h...)
Affinity DataKi:  54nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245168((R)-2-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-...)
Affinity DataKi:  65nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245674(3-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-h...)
Affinity DataKi:  66nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245675(3-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-h...)
Affinity DataKi:  66nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Displayed 1 to 50 (of 93 total ) | Next | Last >>
Jump to: