Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50026742
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.525nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.741nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50272622(2-((S)-2-Hydroxymethylindolin-1-ylmethyl)-melatoni...)
Affinity DataKi:  7.80nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50272622(2-((S)-2-Hydroxymethylindolin-1-ylmethyl)-melatoni...)
Affinity DataKi:  9.80nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50272623((+/-)-2-(2-Hydroxymethylindolin-1-ylmethyl)-melato...)
Affinity DataKi:  17.5nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50272621((+/-)-2-(2-Hydroxymethyl-5-methoxyindolin-1-ylmeth...)
Affinity DataKi:  33.6nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50272621((+/-)-2-(2-Hydroxymethyl-5-methoxyindolin-1-ylmeth...)
Affinity DataKi:  34.5nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50272623((+/-)-2-(2-Hydroxymethylindolin-1-ylmethyl)-melato...)
Affinity DataKi:  36.2nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266406(N-[2-(9-Methoxy-13a,14-dihydro-6H,13H-pyrazino[1,2...)
Affinity DataKi:  65.2nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266406(N-[2-(9-Methoxy-13a,14-dihydro-6H,13H-pyrazino[1,2...)
Affinity DataKi:  319nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266407(N-[2-(2,9-Dimethoxy-13a,14-dihydro-6H,13H-pyrazino...)
Affinity DataKi:  410nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50273283(N-[2-(13a,14-Dihydro-6H,13H-pyrazino[1,2-a;4,5-a']...)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50273283(N-[2-(13a,14-Dihydro-6H,13H-pyrazino[1,2-a;4,5-a']...)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266407(N-[2-(2,9-Dimethoxy-13a,14-dihydro-6H,13H-pyrazino...)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed