Compile Data Set for Download or QSAR
Report error Found 88 Enz. Inhib. hit(s) with all data for entry = 50026627
LigandPNGBDBM50262463((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-7,7-di...)
Affinity DataIC50: 18nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262463((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-7,7-di...)
Affinity DataIC50: 31nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262460((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50: 35nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262460((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50: 49nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262460((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50: 51nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262463((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-7,7-di...)
Affinity DataIC50: 59nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262462((S)-2-(3-(benzo[b]thiophen-3-ylmethyl)morpholino)-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262461(2-(3-((1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)morpho...)
Affinity DataIC50: 63nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262461(2-(3-((1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)morpho...)
Affinity DataIC50: 74nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262461(2-(3-((1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)morpho...)
Affinity DataIC50: 107nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262462((S)-2-(3-(benzo[b]thiophen-3-ylmethyl)morpholino)-...)
Affinity DataIC50: 125nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262408(5,5-dimethyl-2-(3-(naphthalen-1-ylmethyl)morpholin...)
Affinity DataIC50: 126nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262463((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-7,7-di...)
Affinity DataIC50: 199nMAssay Description:Inhibition of PI3K-mediated AKT Ser473 phosphorylation in PTEN negative human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262462((S)-2-(3-(benzo[b]thiophen-3-ylmethyl)morpholino)-...)
Affinity DataIC50: 223nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262408(5,5-dimethyl-2-(3-(naphthalen-1-ylmethyl)morpholin...)
Affinity DataIC50: 229nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262408(5,5-dimethyl-2-(3-(naphthalen-1-ylmethyl)morpholin...)
Affinity DataIC50: 386nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262461(2-(3-((1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)morpho...)
Affinity DataIC50: 481nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50261834(5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benz...)
Affinity DataIC50: 693nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50261834(5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benz...)
Affinity DataIC50: 701nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262407((S)-2-(3-benzylmorpholino)-5,5-dimethyl-5,6-dihydr...)
Affinity DataIC50: 833nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50261834(5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benz...)
Affinity DataIC50: 975nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262463((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-7,7-di...)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262460((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262354(2-(morpholin-4-yl)-6,7-dihydro-4H-spiro[1,3-benzot...)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262353(2-(morpholin-4-yl)-6,7-dihydro-4H-spiro[1,3-benzot...)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262409(5,5-dimethyl-2-(3-(naphthalen-2-ylmethyl)morpholin...)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262463((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-7,7-di...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of PI3K-mediated AKT Ser473 phosphorylation in PTEN negative human PC3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262353(2-(morpholin-4-yl)-6,7-dihydro-4H-spiro[1,3-benzot...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262460((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of PI3K-mediated AKT Ser473 phosphorylation in PTEN negative human PC3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262354(2-(morpholin-4-yl)-6,7-dihydro-4H-spiro[1,3-benzot...)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262409(5,5-dimethyl-2-(3-(naphthalen-2-ylmethyl)morpholin...)
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262354(2-(morpholin-4-yl)-6,7-dihydro-4H-spiro[1,3-benzot...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262407((S)-2-(3-benzylmorpholino)-5,5-dimethyl-5,6-dihydr...)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262407((S)-2-(3-benzylmorpholino)-5,5-dimethyl-5,6-dihydr...)
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262353(2-(morpholin-4-yl)-6,7-dihydro-4H-spiro[1,3-benzot...)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262296(rac-5-methyl-2-morpholino-5,6-dihydrobenzo[d]thiaz...)
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262410((R)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50: 2.53E+3nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262462((S)-2-(3-(benzo[b]thiophen-3-ylmethyl)morpholino)-...)
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262410((R)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50261834(5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benz...)
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of PI3K-mediated AKT Ser473 phosphorylation in PTEN negative human PC3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50261834(5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benz...)
Affinity DataIC50: 3.45E+3nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50262409(5,5-dimethyl-2-(3-(naphthalen-2-ylmethyl)morpholin...)
Affinity DataIC50: 3.49E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262410((R)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262299(2-morpholino-5,6-dihydrobenzo[d]thiazol-7(4H)-one ...)
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262299(2-morpholino-5,6-dihydrobenzo[d]thiazol-7(4H)-one ...)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262357(5,5-dimethyl-2-(pyridin-4-yl)-5,6-dihydrobenzo[d]t...)
Affinity DataIC50: 4.16E+3nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262296(rac-5-methyl-2-morpholino-5,6-dihydrobenzo[d]thiaz...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262296(rac-5-methyl-2-morpholino-5,6-dihydrobenzo[d]thiaz...)
Affinity DataIC50: 5.97E+3nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262354(2-(morpholin-4-yl)-6,7-dihydro-4H-spiro[1,3-benzot...)
Affinity DataIC50: 6.26E+3nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262408(5,5-dimethyl-2-(3-(naphthalen-1-ylmethyl)morpholin...)
Affinity DataIC50: 6.94E+3nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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