Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 2949
TargetAldo-keto reductase family 1 member C1(Human)
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | CHEMBL449129 ...)
Affinity DataKi:  5.90nM ΔG°:  -47.0kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | CHEMBL449129 ...)
Affinity DataKi:  58nM ΔG°:  -41.3kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | CHEMBL449129 ...)
Affinity DataKi:  70nM ΔG°:  -40.8kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C1 [L54V](Human)
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | CHEMBL449129 ...)
Affinity DataKi:  85nM ΔG°:  -40.4kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | CHEMBL449129 ...)
Affinity DataKi:  270nM ΔG°:  -37.5kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | CHEMBL449129 ...)
Affinity DataKi:  2.80E+3nM ΔG°:  -31.7kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C4(Human)
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | CHEMBL449129 ...)
Affinity DataKi:  2.40E+4nM ΔG°:  -26.4kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | CHEMBL449129 ...)
Affinity DataKi:  9.40E+4nM ΔG°:  -23.0kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)