Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50026496
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263242(2-{(2R,3R,4S,5R)-5-[({[(2R,3S,4R,5R)-5-(6-Amino-pu...)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263242(2-{(2R,3R,4S,5R)-5-[({[(2R,3S,4R,5R)-5-(6-Amino-pu...)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataKi:  10nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19267([({[(2R,3S,4R,5R)-5-(6-amino-2-ethyl-9H-purin-9-yl...)
Affinity DataKi:  20nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19267([({[(2R,3S,4R,5R)-5-(6-amino-2-ethyl-9H-purin-9-yl...)
Affinity DataKi:  40nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataKi:  40nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19266([({[(2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-y...)
Affinity DataKi:  70nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19266([({[(2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-y...)
Affinity DataKi:  110nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263243(N-(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-di...)
Affinity DataKi:  170nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263245(N-5-(6-amino-2-ethynyl-9H-purin-9-yl)-3,4-dihydrox...)
Affinity DataKi:  180nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19265([({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-di...)
Affinity DataKi:  250nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263244(N-(((2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-y...)
Affinity DataKi:  310nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19265([({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-di...)
Affinity DataKi:  330nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263243(N-(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-di...)
Affinity DataKi:  350nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263246(N-(((2R,3S,4R,5R)-5-(6-amino-2-ethyl-9H-purin-9-yl...)
Affinity DataKi:  440nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263245(N-5-(6-amino-2-ethynyl-9H-purin-9-yl)-3,4-dihydrox...)
Affinity DataKi:  520nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263244(N-(((2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-y...)
Affinity DataKi:  660nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263246(N-(((2R,3S,4R,5R)-5-(6-amino-2-ethyl-9H-purin-9-yl...)
Affinity DataKi:  820nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263248(7-hydroxy-6-(2-hydroxyethyl)-5-methoxy-4-methyliso...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263247(Mycophenolic bis(sulfonamide) | CHEMBL476562)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263248(7-hydroxy-6-(2-hydroxyethyl)-5-methoxy-4-methyliso...)
Affinity DataKi:  1.54E+4nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263247(Mycophenolic bis(sulfonamide) | CHEMBL476562)
Affinity DataKi:  1.82E+4nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263249(Adenosine 5'-methylenebis(sulfonamide) | CHEMBL476...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50263249(Adenosine 5'-methylenebis(sulfonamide) | CHEMBL476...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed