Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50026408
TargetTranscription factor p65(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252373(Spheciosterol sulfate A | CHEMBL447723)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NF-kappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252376(Topsentiasterol sulfate E | CHEMBL455091)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NF-kappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252375(Spheciosterol sulfate C | CHEMBL446072)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NF-kappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252374(Spheciosterol sulfate B | CHEMBL475118)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NF-kappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252375(Spheciosterol sulfate C | CHEMBL446072)
Affinity DataIC50: 110nMAssay Description:Inhibition of PKCzeta by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252374(Spheciosterol sulfate B | CHEMBL475118)
Affinity DataIC50: 530nMAssay Description:Inhibition of PKCzeta by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252376(Topsentiasterol sulfate E | CHEMBL455091)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of PKCzeta by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252373(Spheciosterol sulfate A | CHEMBL447723)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of PKCzeta by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed