Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50026367
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243346(rac, syn-5-(cyclohex-2-en-1-yl)-7,9-difluoro-2,2,4...)
Affinity DataEC50:  27nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394(rac, syn-7,9-difluoro-5-(3-methylcyclohex-2-en-1-y...)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394(rac, syn-7,9-difluoro-5-(3-methylcyclohex-2-en-1-y...)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243395(rac, anti-7,9-difluoro-5-(3-methylcyclohex-2-en-1-...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394(rac, syn-7,9-difluoro-5-(3-methylcyclohex-2-en-1-y...)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243439(rac, syn-7,9-difluoro-5-(3-methylcyclohex-2-en-1-y...)
Affinity DataEC50:  96nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243440((-)-7,9-difluoro-5-(6-methyl-7-oxa-bicyclo[4.1.0]h...)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243395(rac, anti-7,9-difluoro-5-(3-methylcyclohex-2-en-1-...)
Affinity DataEC50:  5.40nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394(rac, syn-7,9-difluoro-5-(3-methylcyclohex-2-en-1-y...)
Affinity DataEC50:  50.8nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394(rac, syn-7,9-difluoro-5-(3-methylcyclohex-2-en-1-y...)
Affinity DataEC50:  50.8nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243439(rac, syn-7,9-difluoro-5-(3-methylcyclohex-2-en-1-y...)
Affinity DataEC50:  10.7nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243440((-)-7,9-difluoro-5-(6-methyl-7-oxa-bicyclo[4.1.0]h...)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243346(rac, syn-5-(cyclohex-2-en-1-yl)-7,9-difluoro-2,2,4...)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394(rac, syn-7,9-difluoro-5-(3-methylcyclohex-2-en-1-y...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394(rac, syn-7,9-difluoro-5-(3-methylcyclohex-2-en-1-y...)
Affinity DataIC50: 34nMAssay Description:Antagonist activity at human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394(rac, syn-7,9-difluoro-5-(3-methylcyclohex-2-en-1-y...)
Affinity DataIC50: 1.35E+3nMAssay Description:Antagonist activity at human mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243440((-)-7,9-difluoro-5-(6-methyl-7-oxa-bicyclo[4.1.0]h...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394(rac, syn-7,9-difluoro-5-(3-methylcyclohex-2-en-1-y...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394(rac, syn-7,9-difluoro-5-(3-methylcyclohex-2-en-1-y...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243346(rac, syn-5-(cyclohex-2-en-1-yl)-7,9-difluoro-2,2,4...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243395(rac, anti-7,9-difluoro-5-(3-methylcyclohex-2-en-1-...)
Affinity DataKi:  14nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394(rac, syn-7,9-difluoro-5-(3-methylcyclohex-2-en-1-y...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed