Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50035959
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002462(1,3-Diethyl-2-[3-(1,3,3-trimethyl-1,3-dihydro-indo...)
Affinity DataKd:  1.5nMAssay Description:Scatchard analysis at concentration of the 10 uM :Apparent affinity constant (Kd) against tachykinin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002462(1,3-Diethyl-2-[3-(1,3,3-trimethyl-1,3-dihydro-indo...)
Affinity DataKd:  0.180nMAssay Description:Scatchard analysis at concentration of the 3 uM :Apparent affinity constant (Kd) against tachykinin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002462(1,3-Diethyl-2-[3-(1,3,3-trimethyl-1,3-dihydro-indo...)
Affinity DataKd:  0.970nMAssay Description:Scatchard analysis at concentration of the 1 uM :Apparent affinity constant (Kd) against tachykinin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009228(CHEMBL413846 | SP (substance P) | Spantide)
Affinity DataIC50: 0.120nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009225(CHEMBL300854 | 3-Ethyl-1-(3-hydroxy-propyl)-2-[3-(...)
Affinity DataIC50: 350nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009226(CHEMBL48734 | 1,3-Diethyl-2-[3-(1-ethyl-3,3-dimeth...)
Affinity DataIC50: 390nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009234(CHEMBL416468 | 1-(3-Acetoxy-propyl)-3-ethyl-2-[3-(...)
Affinity DataIC50: 410nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002454(CHEMBL386306 | D-Lys(Nicotinoyl)-Pro(3-Pyridyl)-Al...)
Affinity DataIC50: 500nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002462(1,3-Diethyl-2-[3-(1,3,3-trimethyl-1,3-dihydro-indo...)
Affinity DataIC50: 510nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009235(CHEMBL295686 | 1,3-Diethyl-2-[3-(3-methyl-3H-benzo...)
Affinity DataIC50: 700nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009227(CHEMBL295781 | 1-(3-Ethoxycarbonyl-propyl)-3-ethyl...)
Affinity DataIC50: 850nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009233(CHEMBL52114 | 1,3-Diethyl-2-[3-(1-methyl-2a,5-dihy...)
Affinity DataIC50: 850nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009237(CHEMBL49233 | 1,3-Diethyl-2-{3-[1-(2-hydroxy-ethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009231(CHEMBL301168 | 6,7-Dichloro-1,3-diethyl-2-[3-(1,3,...)
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009236(CHEMBL48173 | 1-(3-Dimethylamino-propyl)-3-ethyl-2...)
Affinity DataIC50: 1.30E+3nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009229(CHEMBL301946 | 1-(3-Carboxy-propyl)-3-ethyl-2-[3-(...)
Affinity DataIC50: 1.40E+3nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009230(CHEMBL51135 | 1,3-Diethyl-2-[3-(3-methyl-thiazolid...)
Affinity DataIC50: 1.60E+3nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002462(1,3-Diethyl-2-[3-(1,3,3-trimethyl-1,3-dihydro-indo...)
Affinity DataIC50: 1.70E+3nMAssay Description:Binding affinity of compound was evaluated towards tachykinin receptor 2 by using radioligand ([125I]-NKA in rat duodenumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009232(CHEMBL48454 | 1-Carbamoylmethyl-3-ethyl-2-[3-(1,3,...)
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009223(CHEMBL52448 | 2-[3-(1-Dimethylcarbamoylmethyl-3,3-...)
Affinity DataIC50: 2.60E+3nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002462(1,3-Diethyl-2-[3-(1,3,3-trimethyl-1,3-dihydro-indo...)
Affinity DataIC50: 3.30E+3nMAssay Description:Binding affinity of compound was evaluated towards tachykinin receptor 3 by using radioligand [1261]eledoisin in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50009238(CHEMBL296134 | 1,3-Diethyl-2-(4-pyrrolidin-1-yl-bu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed