Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50035945
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
Affinity DataKi:  0.260nMAssay Description:Binding affinity of compound was measured against Opioid receptor kappa 1 on electrically stimulated guinea pig ileal longitudinal muscle myenteric p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009129(binaltorphimine(BNI))
Affinity DataKi:  0.410nMAssay Description:Binding affinity against Opioid receptor kappa 1 was measured in the guinea pig brain membranes using [3H]EK in the presence of 1 uM unlabeled DAMGO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009127(bis(4-cyclopropylmethyl-12-oxa-4-azapentacyclo[9.6...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity of compound was measured against Opioid receptor kappa 1 on electrically stimulated guinea pig ileal longitudinal muscle myenteric p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009130(bis(4-cyclopropylmethyl-12-oxa-4-azapentacyclo[9.6...)
Affinity DataKi:  10nMAssay Description:Binding affinity against Opioid receptor delta 1 was measured in the guinea pig brain membranes using [3H]DADLE in the presence of 1 uM unlabeled DAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009130(bis(4-cyclopropylmethyl-12-oxa-4-azapentacyclo[9.6...)
Affinity DataKi:  10nMAssay Description:Binding affinity against Opioid receptor kappa 1 was measured in the guinea pig brain membranes using [3H]EK in the presence of 1 uM unlabeled DAMGO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009129(binaltorphimine(BNI))
Affinity DataKi:  18nMAssay Description:Binding affinity against Opioid receptor mu 1 was measured in the guinea pig brain membranes using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009130(bis(4-cyclopropylmethyl-12-oxa-4-azapentacyclo[9.6...)
Affinity DataKi:  29nMAssay Description:Binding affinity against Opioid receptor mu 1 was measured in the guinea pig brain membranes using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
Affinity DataKi:  39nMAssay Description:Binding affinity against Opioid receptor delta 1 was measured in the guinea pig brain membranes using [3H]DADLE in the presence of 1 uM unlabeled DAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
Affinity DataKi:  47nMAssay Description:Binding affinity against Opioid receptor mu 1 was measured in the guinea pig brain membranes using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009129(binaltorphimine(BNI))
Affinity DataKi:  58nMAssay Description:Binding affinity against Opioid receptor delta 1 was measured in the guinea pig brain membranes using [3H]DADLE in the presence of 1 uM unlabeled DAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009127(bis(4-cyclopropylmethyl-12-oxa-4-azapentacyclo[9.6...)
Affinity DataKi:  77nMAssay Description:Binding affinity against Opioid receptor delta 1 was measured in the guinea pig brain membranes using [3H]DADLE in the presence of 1 uM unlabeled DAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009127(bis(4-cyclopropylmethyl-12-oxa-4-azapentacyclo[9.6...)
Affinity DataKi:  189nMAssay Description:Binding affinity against Opioid receptor mu 1 was measured in the guinea pig brain membranes using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed