Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50004445
TargetDNA gyrase subunit A(Escherichia coli)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM50045004(9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-ox...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase GyrA/GyrBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM50366824(Avelox | MOXIFLOXACIN | Moxifl-oxacin)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase GyrA/GyrBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM50366824(Avelox | MOXIFLOXACIN | Moxifl-oxacin)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase GyrA/GyrBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Escherichia coli)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM50296358(enofloxacin | 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Escherichia coli DNA gyrase GyrA/GyrBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM50045004(9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-ox...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase GyrA/GyrBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM50296358(enofloxacin | 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1...)
Affinity DataIC50: 1.56E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase GyrA/GyrBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM21691(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridi...)
Affinity DataIC50: 2.15E+5nMAssay Description:Inhibition of Escherichia coli DNA gyrase GyrA/GyrBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM21691(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridi...)
Affinity DataIC50: 4.75E+6nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase GyrA/GyrBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed