Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50025969
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261522(c[hGlu22-Lys26][Gly8]GLP-1(7-37)-NH2 | CHEMBL50764...)
Affinity DataEC50:  0.00400nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50241203(exenatide | HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGSPPP...)
Affinity DataEC50:  0.00400nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261512(Glu20-Lys24][Gly8][GLP-1(7-37)-NH2 | CHEMBL524538)
Affinity DataEC50:  0.450nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261513(c[Glu21-Lys25][Gly8]GLP-1(7-37)-NH2 | CHEMBL525956)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261514(c[Glu24-Lys28][Gly8]GLP-1(7-37)-NH2 | CHEMBL505224)
Affinity DataEC50:  0.740nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261515(c[Glu22-Lys26][Gly8]GLP-1(7-37)-NH2 | CHEMBL524907)
Affinity DataEC50:  0.0100nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261516(c[Glu23-Lys27][Gly8]GLP-1(7-37)-NH2 | CHEMBL499133)
Affinity DataEC50:  0.00800nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261517(c[Glu25-Lys29][Gly8]GLP-1(7-37)-NH2 | CHEMBL504759)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261508([Gly8,Glu22]GLP-1(7,37)-NH2 | CHEMBL525934)
Affinity DataEC50:  0.00300nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261509([Gly8, aib22]GLP-1(7-37)-NH2 | CHEMBL499370)
Affinity DataEC50:  0.0270nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261510(c[Glu18-Lys22][Gly8]GLP-1(7-37)-NH2 | CHEMBL499208)
Affinity DataEC50:  0.00600nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261511(c[Glu19-Lys23][Gly8]GLP-1(7-37)-NH2 | CHEMBL507190)
Affinity DataEC50:  0.0770nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261523(c[beta-hGlu22-Lys26][Gly8]GLP-1(7-37)-NH2 | CHEMBL...)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261524(c[Glu21-Lys26][Gly8]GLP-1(7-37)-NH2 | CHEMBL526893)
Affinity DataEC50:  0.470nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261525(c[Cpa19-Lys26][Gly8]GLP-1(7-37)-NH2 | CHEMBL468769)
Affinity DataEC50:  9nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261521(c[Asp22-Lys26][Gly8]GLP-1(7-37)-NH2 | CHEMBL526684)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261520(c[Glu22-Orn26][Gly8]GLP-1(7-37)-NH2 | CHEMBL526730)
Affinity DataEC50:  0.0190nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261506(HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG-NH2 | CHEMBL499930)
Affinity DataEC50:  0.00600nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261507([Gly8]GLP-1(7-37)-NH2 | CHEMBL526685)
Affinity DataEC50:  0.0140nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261519(c[Glu22-Lys26][Gly8]GLP-1(7-37)-NH2 | CHEMBL527077)
Affinity DataEC50:  0.00800nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261518(c[Glu26-Lys30][Gly8]GLP-1(7-37)-NH2 | CHEMBL500447)
Affinity DataEC50:  0.0240nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50241203(exenatide | HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGSPPP...)
Affinity DataIC50: 0.660nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261508([Gly8,Glu22]GLP-1(7,37)-NH2 | CHEMBL525934)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261506(HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG-NH2 | CHEMBL499930)
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261516(c[Glu23-Lys27][Gly8]GLP-1(7-37)-NH2 | CHEMBL499133)
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261515(c[Glu22-Lys26][Gly8]GLP-1(7-37)-NH2 | CHEMBL524907)
Affinity DataIC50: 2.10nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261519(c[Glu22-Lys26][Gly8]GLP-1(7-37)-NH2 | CHEMBL527077)
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261507([Gly8]GLP-1(7-37)-NH2 | CHEMBL526685)
Affinity DataIC50: 2.80nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261509([Gly8, aib22]GLP-1(7-37)-NH2 | CHEMBL499370)
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261510(c[Glu18-Lys22][Gly8]GLP-1(7-37)-NH2 | CHEMBL499208)
Affinity DataIC50: 3.60nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261522(c[hGlu22-Lys26][Gly8]GLP-1(7-37)-NH2 | CHEMBL50764...)
Affinity DataIC50: 6.20nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261520(c[Glu22-Orn26][Gly8]GLP-1(7-37)-NH2 | CHEMBL526730)
Affinity DataIC50: 6.40nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261518(c[Glu26-Lys30][Gly8]GLP-1(7-37)-NH2 | CHEMBL500447)
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261511(c[Glu19-Lys23][Gly8]GLP-1(7-37)-NH2 | CHEMBL507190)
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261512(Glu20-Lys24][Gly8][GLP-1(7-37)-NH2 | CHEMBL524538)
Affinity DataIC50: 26nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261513(c[Glu21-Lys25][Gly8]GLP-1(7-37)-NH2 | CHEMBL525956)
Affinity DataIC50: 60nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261521(c[Asp22-Lys26][Gly8]GLP-1(7-37)-NH2 | CHEMBL526684)
Affinity DataIC50: 64nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261524(c[Glu21-Lys26][Gly8]GLP-1(7-37)-NH2 | CHEMBL526893)
Affinity DataIC50: 210nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261514(c[Glu24-Lys28][Gly8]GLP-1(7-37)-NH2 | CHEMBL505224)
Affinity DataIC50: 290nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261523(c[beta-hGlu22-Lys26][Gly8]GLP-1(7-37)-NH2 | CHEMBL...)
Affinity DataIC50: 500nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261517(c[Glu25-Lys29][Gly8]GLP-1(7-37)-NH2 | CHEMBL504759)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50261525(c[Cpa19-Lys26][Gly8]GLP-1(7-37)-NH2 | CHEMBL468769)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed