Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50004444
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50164648(thymidine 5'-(tetrahydrogen triphosphate) | dTTP |...)
Affinity DataKd:  6.71E+4nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase assessed as incorporation of dTMP by burst assay using RNA/DNA Pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50164648(thymidine 5'-(tetrahydrogen triphosphate) | dTTP |...)
Affinity DataKd:  1.44E+5nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase M184V mutant assessed as incorporation of dTMP by burst assay usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50370655(CHEMBL485652)
Affinity DataKd:  6.05E+5nMAssay Description:Inhibition of DNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase M184V mutant assessed as incorporation of d4TMP by burst assay usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50370655(CHEMBL485652)
Affinity DataKd:  4.08E+4nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase assessed as incorporation of d4TMP by burst assay using RNA/DNA Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50483018(CHEMBL485651)
Affinity DataKd:  1.68E+5nMAssay Description:Inhibition of DNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase M184V mutant assessed as incorporation of 4-EdTMP by burst assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50483018(CHEMBL485651)
Affinity DataKd:  1.14E+4nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase assessed as incorporation of 4-EdTMP by burst assay using RNA/DNA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50164648(thymidine 5'-(tetrahydrogen triphosphate) | dTTP |...)
Affinity DataKd:  7.32E+4nMAssay Description:Inhibition of DNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase M184V mutant assessed as incorporation of dTMP by burst assay usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50370655(CHEMBL485652)
Affinity DataKd:  4.80E+4nMAssay Description:Inhibition of DNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase assessed as incorporation of d4TMP by burst assay using DNA/DNA Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50370655(CHEMBL485652)
Affinity DataKd:  2.32E+5nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase M184V mutant assessed as incorporation of d4TMP by burst assay usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50483018(CHEMBL485651)
Affinity DataKd:  4.34E+4nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase M184V mutant assessed as incorporation of 4-EdTMP by burst assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50164648(thymidine 5'-(tetrahydrogen triphosphate) | dTTP |...)
Affinity DataKd:  1.54E+4nMAssay Description:Inhibition of DNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase assessed as incorporation of dTMP by burst assay using DNA/DNA Pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50483018(CHEMBL485651)
Affinity DataKd:  1.58E+4nMAssay Description:Inhibition of DNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase assessed as incorporation of 4-EdTMP by burst assay using DNA/DNA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed