Compile Data Set for Download or QSAR
Report error Found 105 Enz. Inhib. hit(s) with all data for entry = 50041539
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411769(CHEMBL403390)
Affinity DataIC50: 0.398nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411838(CHEMBL271276)
Affinity DataIC50: 0.398nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411851(CHEMBL257880)
Affinity DataIC50: 0.794nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411829(CHEMBL404237)
Affinity DataIC50: 1.26nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411839(CHEMBL271477)
Affinity DataIC50: 2.51nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411767(CHEMBL402082)
Affinity DataIC50: 3.16nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411771(CHEMBL257879)
Affinity DataIC50: 3.16nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411823(CHEMBL271065)
Affinity DataIC50: 6.31nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411763(CHEMBL438156)
Affinity DataIC50: 7.94nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411775(CHEMBL272800)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411824(CHEMBL271275)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411844(CHEMBL411499)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411802(CHEMBL258050)
Affinity DataIC50: 12.6nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411809(CHEMBL271093)
Affinity DataIC50: 12.6nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411770(CHEMBL408041)
Affinity DataIC50: 15.8nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411812(CHEMBL270400)
Affinity DataIC50: 15.8nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411826(CHEMBL273025)
Affinity DataIC50: 15.8nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411837(CHEMBL414000)
Affinity DataIC50: 15.8nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411768(CHEMBL255402)
Affinity DataIC50: 19.9nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411803(CHEMBL428778)
Affinity DataIC50: 19.9nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411806(CHEMBL429781)
Affinity DataIC50: 19.9nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411845(CHEMBL404883)
Affinity DataIC50: 19.9nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411810(CHEMBL257882)
Affinity DataIC50: 25.1nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411840(CHEMBL256455)
Affinity DataIC50: 31.6nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411793(CHEMBL257223)
Affinity DataIC50: 39.8nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411830(CHEMBL404238)
Affinity DataIC50: 39.8nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411778(CHEMBL401869)
Affinity DataIC50: 50.1nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411780(CHEMBL406954)
Affinity DataIC50: 50.1nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411825(CHEMBL271274)
Affinity DataIC50: 50.1nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411846(CHEMBL402733)
Affinity DataIC50: 50.1nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411847(CHEMBL405018)
Affinity DataIC50: 50.1nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411777(CHEMBL428426)
Affinity DataIC50: 63.1nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411790(CHEMBL401794)
Affinity DataIC50: 63.1nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411761(CHEMBL257314)
Affinity DataIC50: 79.4nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411781(CHEMBL401977)
Affinity DataIC50: 79.4nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411789(CHEMBL538165)
Affinity DataIC50: 79.4nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411827(CHEMBL272069)
Affinity DataIC50: 79.4nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411759(CHEMBL258263)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411811(CHEMBL257881)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411828(CHEMBL270167)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411841(CHEMBL257222)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411856(CHEMBL255958)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411804(CHEMBL258293)
Affinity DataIC50: 126nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411822(CHEMBL257699)
Affinity DataIC50: 126nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411842(CHEMBL403362)
Affinity DataIC50: 126nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411860(CHEMBL403607)
Affinity DataIC50: 126nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411792(CHEMBL256423)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411805(CHEMBL272940)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411821(CHEMBL403338)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
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